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- Title
Management of Candida infections in liver transplant recipients: current perspectives.
- Authors
Lingegowda, Pushpalatha B.; Tan, Ban Hock
- Abstract
Liver transplantation has emerged as a widely accepted lifesaving therapeutic option for many patients with a variety of liver diseases. Improved surgical and medical management has led to significant improvements in post-transplant survival rates with a 1 year and 5 year patient survival of 87% and 73%, respectively. A high mortality rate due to infections during the first post-transplant year persists. Invasive candidiasis is recognized as a significant problem associated with high morbidity and mortality. Recent surveillance data has helped to understand the changes in the epidemiology and the evolving trends in the use of antifungal agents for prophylaxis and treatment combined with the challenges of managing these invasive fungal infections, which has led the transplant community to explore the best management strategies. The emergence of resistant fungi and excess costs in managing these invasive fungal infections has added to the complexities of management. In this context, current perspectives in the management of Candida infections in liver transplant recipients will be reviewed.
- Subjects
CANDIDIASIS; LIVER transplantation; SURGICAL complications; LIVER diseases; EPIDEMIOLOGY; MYCOSES; PATIENTS
- Publication
Psychology Research & Behavior Management, 2014, Vol 7, p45
- ISSN
1179-1578
- Publication type
Article
- DOI
10.2147/TRRM.S38620