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- Title
Identification and target prediction of small miRNA.
- Authors
Ranjith Raj, V. P. R. B.; Vishnupriya, V.; Gayathri, R.
- Abstract
Aim: The aim of the study was to identify, target, and predict small miRNA. Materials and Methods: Small RNA with <50 nucleotides long non-coding RNA has various functions such as gene regulation, we took one such RNA from non-coding RNA database from NCBI and analyzed its structure and function. Quality of small RNA sequencing data of Drosophila melanogaster downloaded from NCBI was checked using next-generation sequencing, FastQC and adapters were removed using cutadapt tool. The quality check was performed before and after trimming. Results: From the data, we have obtained the miRNA which had the highest score seemed to have many regulatory functions and it is surprising to know how one miRNA could be responsible for 10 important functions. Conclusion: Earlier it was considered that the exon part was more clinically significant, but the current trend is that the miRNA which is obtained from the intron part is of equal importance and has a lot of clinical significance which could be discovered in future large scale researches.
- Subjects
MICRORNA; NON-coding RNA; NUCLEOTIDE sequence; DROSOPHILA melanogaster; NUCLEOTIDE sequencing; INTRONS; ADAPTERS (Telecommunication); NEXT generation networks
- Publication
Drug Invention Today, 2019, Vol 11, Issue 7, p1571
- ISSN
0975-7619
- Publication type
Article