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- Title
Asymptomatic hyperuricemia: the case for conservative management.
- Authors
Liang, Matthew H.; Fries, James F.; Liang, M H; Fries, J F
- Abstract
The management of asymptomatic hyperuricemia is controversial. Reported benefits from treatment prevention of acute gouty arthritis, chronic tophaceous gout, urolithiasis, or gouty nephropathy. A review of experimental and clinical data suggests that the risks of asymptomatic hyperuricemia are small or unknown and the efficacy of long-term treatment in preventing gout or renal disease is unproved. The costs and risks of prolonged drug administration and practical considerations such as patient compliance mitigate against long-term therapy in asymptomatic persons. We offer some recommendations for an expectant approach to the management of asymptomatic hyperuricemia.
- Subjects
HYPERURICEMIA; GOUT; GOUT diagnosis; KIDNEY stones diagnosis; URIC acid; RELATIVE medical risk
- Publication
Annals of Internal Medicine, 1978, Vol 88, Issue 5, p666
- ISSN
0003-4819
- Publication type
journal article
- DOI
10.7326/0003-4819-88-5-666