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- Title
Clinicopathological findings, treatment, and outcome in 60 cats with gastrointestinal eosinophilic sclerosing fibroplasia.
- Authors
Černá, Petra; Lopez‐Jimenez, Cristobal; Fukushima, Kenjiro; Nakashima, Ko; Nakagawa, Taisuke; Adam, Fiona; Groth, Anna; Denning, Andrew; Israeliantz, Nicolas; Gunn‐Moore, Danièlle A.
- Abstract
Background: Gastrointestinal eosinophilic sclerosing fibroplasia (GESF) in cats presents as mass(es) associated with the gastrointestinal tract, mesentery, and abdominal lymph nodes. Hypothesis/Objectives: To report the clinicopathological findings, treatment, and outcome of cats with GESF. Animals: Sixty client‐owned cats diagnosed with GESF. Methods: Retrospective review of medical records of cats with histopathologically confirmed GESF. Results: The median age was 5.4 years (interquartile range [IQR], 3.3‐8.9.); 30% were Domestic Shorthairs and 12% were Domestic Longhair cats, with the most prevalent pedigree breeds being Ragdolls (25%), Exotic Shorthair (10%) and Persian (8%) cats. The median duration of clinical signs was 90 days (IQR, 17.5‐247.0); the most common clinical signs were weight loss (60%), hyporexia/anorexia (55%), chronic vomiting (37%), lethargy (35%) and chronic diarrhea (27%). Masses were located in the small intestine (32%), stomach (27%), ileocolic junction (15%), colon (10%), lymph node (8%) and mesentery (8%) and 15% of cats had >1 mass. Eosinophilia was present in 50% and hypoalbuminemia in 28% of cats. The mass was removed surgically in 37% of cases. Most cats (98%) were treated with corticosteroids. Survival was not statistically different between cats treated with surgical resection and cats treated with medical therapy alone, 88% of the cats were still alive at the time of writing. Conclusions and Clinical Importance: GESF is an important differential diagnosis for abdominal masses in cats, and has a much better prognosis than previously reported.
- Subjects
CATS; CLINICAL pathology; SMALL intestine; GASTROINTESTINAL system; LYMPH nodes; PET owners
- Publication
Journal of Veterinary Internal Medicine, 2024, Vol 38, Issue 2, p1005
- ISSN
0891-6640
- Publication type
Article
- DOI
10.1111/jvim.16992