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- Title
Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes.
- Authors
Flethøj, M.; Schwarzwald, C.C.; Haugaard, M.M.; Carstensen, H.; Kanters, J.K.; Olsen, L.H.; Buhl, R.
- Abstract
Background Prolonged exercise in human athletes is associated with transient impairment of left ventricular ( LV) function, known as cardiac fatigue. Cardiac effects of prolonged exercise in horses remain unknown. Objectives To investigate the effects of prolonged exercise on LV systolic and diastolic function in horses. Animals Twenty-six horses competing in 120-160 km endurance rides. Methods Cross-sectional field study. Echocardiography was performed before and after rides, and the following morning, and included two-dimensional echocardiography, anatomical M-mode, pulsed-wave tissue Doppler imaging, and two-dimensional speckle tracking. Correlation between echocardiographic variables and cardiac troponin I was evaluated. Results Early diastolic myocardial velocities decreased significantly in longitudinal (baseline: −17.4 ± 2.4cm/s; end of ride: −15.8 ± 3.2cm/s ( P = .013); morning after: −15.4 ± 3.0cm/s ( P = .0033)) and radial directions (−32.8 ± 3.4cm/s; −28.1 ± 5.8cm/s ( P < .001); −26.4 ± 5.5cm/s ( P < .001)). Early diastolic strain rates decreased significantly in longitudinal (1.58 ± 0.27s−1; 1.45 ± 0.26s−1 ( P = .036); 1.41 ± 0.25s−1 ( P = .013)) and circumferential directions (2.43 ± 0.29s−1; 1.96 ± 0.46s−1 ( P < .001); 2.11 ± 0.32s−1 ( P < .001)). Systolic variables showed ambiguous results. No correlations with serum cardiac troponin I concentrations were evident. Conclusions and Clinical Importance Prolonged exercise in horses is associated with impaired LV diastolic function. Reduced ventricular filling persisted for 7-21 hours despite normalization of biochemical indicators of hydration status, indicating that the observed changes were not entirely related to altered preload conditions. The clinical relevance of cardiac fatigue in horses remains uncertain.
- Subjects
ENDURANCE horses; HORSE exercises; LEFT heart ventricle; HEART physiology; MUSCLE fatigue; VETERINARY echocardiography
- Publication
Journal of Veterinary Internal Medicine, 2016, Vol 30, Issue 4, p1260
- ISSN
0891-6640
- Publication type
Article
- DOI
10.1111/jvim.13982