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- Title
Validation of the scored Patient‐Generated Subjective Global Assessment Short Form as a prognostic tool for incurable cancer patients.
- Authors
Cunha, Marcela Souza; Wiegert, Emanuelly Varea Maria; Calixto‐Lima, Larissa; de Oliveira, Livia Costa
- Abstract
Background: The Patient‐Generated Subjective Global Assessment Short Form (PG‐SGA SF) is a standardized tool for assessing nutrition risk in patients with cancer. The aim of this study was to propose and validate a cutoff point for the PG‐SGA SF related to the prognosis of patients with incurable cancer in exclusive palliative care. Methods: This is a prospective cohort study of patients with incurable cancer at the National Cancer Institute in Brazil. A total sample (n = 2,144) was randomly divided into groups: (1) training (n = 1,072), to determine the most accurate PG‐SGA SF cutoff, and (2) validation (n = 1,072), to test the predictive accuracy of this cutoff point. The receiver operating characteristic curve was plotted to determine the best cutoff point of the PG‐SGA SF related to death. Concordance statistics (C statistic) were used to test the predictive accuracy of the models. Kaplan‐Meier curve and the Cox hazard model were used to verify a prognostic value of the cutoff point. Results: PG‐SGA SF score ≥15 was found to be the best cutoff based on 90‐day mortality with good accuracy discrimination (C statistic ≥ 0.74). Patients whose PG‐SGA SF score was ≥15 had a shorter survival of 32 (interquartile range [IQR], 12–75) vs 83 days (IQR, 31–90) (p‐value <.001) and higher risk of death (hazard ratio: 2.20; 95% CI, 1.64–2.95). Conclusions: The proposed PG‐SGA SF cutoff score is valid and, alongside its usefulness in nutrition triage, could provide prognostic value for patients with incurable cancer.
- Subjects
MALNUTRITION; PALLIATIVE treatment; PROGNOSTIC tests; CANCER; CANCER patients
- Publication
JPEN Journal of Parenteral & Enteral Nutrition, 2022, Vol 46, Issue 4, p915
- ISSN
0148-6071
- Publication type
Article
- DOI
10.1002/jpen.2251