We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
EFFECTS OF DIETARY SUPPLEMENTATION OF FISH OIL ON GLUCOLIPID METABOLISM AMONG POSTMENOPAUSAL WOMEN WITH TYPE-2 DIABETES AND HYPERTRIGLYCERIDAEMIA.
- Authors
Hui Xia; Yanyan Wang; Xian Yang; LigangYang; Feng Wang; Huali Tang; Guiju Sun
- Abstract
The purpose of this study was to investigate the effects of deep-sea fish oil on metabolic variables among postmenopausal women with type-2 diabetes mellitus (T2DM) and hypertriglyceridemia. This was a double-blinded randomized placebo-controlled trial, 32 postmenopausal women with T2DM) were included, assigned to an intervention of 4 g fish oil capsules/d (620mg total n-3 PUFA per capsule), or a placebo of 4 g corn oil capsules/d duration 6 months. Physical examination and biochemical detection, referring to blood glucose, lipid indexes and serum n-3 PUFA concentration, were administered after 3- and 6-month intervention, respectively. Following treatment with fish oil, serum high-density lipoprotein (HDL) level (P=0.009) increased, meanwhile serum triglyceride (TG) level decreased after two stage interventions with 0.20±1.07 mmol/L significant decrease. The serum fasting blood glucose (FBG) level decreased notably (P=0.04l) after 3 months with 8.91+2.59 mrnol/L, compared to control group with 9.84±2.65 mmol/L. Furthermore, differential of serum TG level decreased significantly after 6 versus 3 months of intervention, and serum HDL level increased significantly as well. After 6 months, serum DHA (from 2.44+2.19 mmol/L to 4.63± 1.16 mmol/L) a?id EPA (from 1.12+1.59 mmol/L to 2.28±0.90 mmol/L) levels increased significantly (P<0.001). Fish oil can be the adjuvant therapy means to control the serum lipids and glucose among postmenopausal T2DM women with hypertriglyceridemia.
- Subjects
DIETARY supplements; POSTMENOPAUSE; PEOPLE with diabetes; HYPERTRIGLYCERIDEMIA; BLOOD sugar; HIGH density lipoproteins; PHYSIOLOGY
- Publication
Current Topics in Nutraceutical Research, 2017, Vol 15, Issue 3/4, p141
- ISSN
1540-7535
- Publication type
Article