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- Title
The immunodepressive effect of Friend virus: III. EFFECTS ON SPLEEN T CELLS.
- Authors
Dracott, B.N.; Wedderburn, Nina; Doenhoff, M.J.
- Abstract
Examines various types of T lymphocyte functions in the spleens of mice infected four days previously with Friend virus (FV) in order to analyze its effect on the antibody response. Finding that infection does not reduce the percentage of T lymphocytes in the spleen, nor the ability to respond to phytohemagglutinin (PHA); Results suggesting that FV does not affect spleen T lymphocyte proliferation or helper function; Conclusion that the immune defect resides in the B lymphocytes.
- Subjects
T cells; SPLEEN; FRIEND virus; IMMUNOGLOBULINS; PHYTOHEMAGGLUTININS; B cells
- Publication
Immunology, 1977, Vol 33, Issue 4, p573
- ISSN
0019-2805
- Publication type
Article