We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Synthesis and Biological Evaluation of Some Novel 1,8-Naphthyridine Derivatives.
- Authors
Abu-Melha, Sraa
- Abstract
A series of substituted 1,8-naphthyridine derivatives was synthesized to be used as cytotoxic and antioxidant agents by applying 1,4-dihydro-4-oxo-1,8-naphthyridine-3-carbohydrazide (1) as the starting material. Compound 1 was reacted with different reagents to afford the corresponding 3-heterarylcarbonyl-1,8-naphthyridine derivatives 3-19 which were tested for their in vitro cytotoxicity against Ehrlich Ascites Carcinoma, and antioxidant activity. Compound 15 showed the best cytotoxicity and antioxidant activity.
- Subjects
NAPHTHYRIDINES; HETEROCYCLIC compounds; ANTIOXIDANTS; CARBOHYDRATE analysis; MOLECULAR structure
- Publication
Acta Chimica Slovenica, 2017, Vol 64, Issue 4, p919
- ISSN
1318-0207
- Publication type
Article
- DOI
10.17344/acsi.2017.3617