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GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation.
Published in:
EMBO Journal, 2004, v. 23, n. 14, p. 2821, doi. 10.1038/sj.emboj.7600297
By:
- Usui, Isao;
- Imamura, Takeshi;
- Satoh, Hiroaki;
- Huang, Jie;
- Babendure, Jennie L.;
- Hupfeld, Christopher J.;
- Olefsky, Jerrold M.
Publication type:
Article
Increased Number of Mucosal-Associated Invariant T Cells Is Associated with the Inhibition of Nonalcoholic Fatty Liver Disease in High Fat Diet–Fed Mice.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 15309, doi. 10.3390/ijms232315309
By:
- Kishi, Haruka;
- Usui, Isao;
- Jojima, Teruo;
- Fujisaka, Shiho;
- Wakamatsu, Sho;
- Mizunuma-Inoue, Yuiko;
- Niitani, Takafumi;
- Sakurai, Shintaro;
- Iijima, Toshie;
- Tomaru, Takuya;
- Tobe, Kazuyuki;
- Aso, Yoshimasa
Publication type:
Article
The SGLT2 Inhibitor Canagliflozin Prevents Carcinogenesis in a Mouse Model of Diabetes and Non-Alcoholic Steatohepatitis-Related Hepatocarcinogenesis: Association with SGLT2 Expression in Hepatocellular Carcinoma.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 20, p. 5237, doi. 10.3390/ijms20205237
By:
- Jojima, Teruo;
- Wakamatsu, Sho;
- Kase, Masato;
- Iijima, Toshie;
- Maejima, Yuko;
- Shimomura, Kenju;
- Kogai, Takahiko;
- Tomaru, Takuya;
- Usui, Isao;
- Aso, Yoshimasa
Publication type:
Article
Adenovirus-mediated chronic "hyper-resistinemia" leads to in vivo insulin resistance in normal rats.
Published in:
Journal of Clinical Investigation, 2004, v. 114, n. 2, p. 224, doi. 10.1172/JCI200420785
By:
- Satoh, Hiroaki;
- Nguyen, M. T. Audrey;
- Miles, Philip D. G.;
- Imamura, Takeshi;
- Usui, Isao;
- Olefsky, Jerrold M.
Publication type:
Article
Adenovirus-mediated chronic "hyper-resistinemia" leads to in vivo insulin resistance in normal rats.
Published in:
2004
By:
- Satoh, Hiroaki;
- Nguyen, M T Audrey;
- Miles, Philip D G;
- Imamura, Takeshi;
- Usui, Isao;
- Olefsky, Jerrold M
Publication type:
journal article
Acute Exacerbation of Anemia with Parvovirus B19 Infection One Year after Sleeve Gastrectomy for Severe Obesity.
Published in:
Internal Medicine, 2022, v. 61, n. 17, p. 2631, doi. 10.2169/internalmedicine.8446-21
By:
- Toshimitsu Shinzawa;
- Isao Usui;
- Kanako Hanawa;
- Hayato Kajitani;
- Shintaro Sakurai;
- Takuya Tomaru;
- Toshie Iijima;
- Teruo Jojima;
- Kazuyuki Kojima;
- Yoshimasa Aso
Publication type:
Article
PACAP Attenuates NMDA-Induced Retinal Damage in Association with Modulation of the Microglia/Macrophage Status into an Acquired Deactivation Subtype.
Published in:
Journal of Molecular Neuroscience, 2013, v. 51, n. 2, p. 493, doi. 10.1007/s12031-013-0017-5
By:
- Wada, Yoshihiro;
- Nakamachi, Tomoya;
- Endo, Kimi;
- Seki, Tamotsu;
- Ohtaki, Hirokazu;
- Tsuchikawa, Daisuke;
- Hori, Motohide;
- Tsuchida, Masashi;
- Yoshikawa, Akira;
- Matkovits, Attila;
- Kagami, Nobuyuki;
- Imai, Nori;
- Fujisaka, Shiho;
- Usui, Isao;
- Tobe, Kazuyuki;
- Koide, Ryohei;
- Takahashi, Haruo;
- Shioda, Seiji
Publication type:
Article
Acute effect of add-on therapy with tofogliflozin, a sodium glucose co-transporter 2 inhibitor, on 24-hours glucose profile and glycaemic variability evaluated by continuous glucose monitoring in patients with type 2 diabetes receiving dipeptidyl peptidase-4 inhibitors.
Published in:
2021
By:
- Iijima, Toshie;
- Hosonuma, Soichiro;
- Kurai, Hidetaka;
- Kajitani, Hayato;
- Sakurai, Shintaro;
- Tomaru, Takuya;
- Jojima, Teruo;
- Usui, Isao;
- Aso, Yoshimasa
Publication type:
journal article
Comparison of insulin degludec (IDeg)/insulin Aspart (IAsp) co‐formulation therapy twice‐daily with free combination of GLP‐1 receptor agonist liraglutide plus insulin degludec in Tochigi: IDEAL Trial.
Published in:
International Journal of Clinical Practice, 2021, v. 75, n. 4, p. 1, doi. 10.1111/ijcp.13734
By:
- Aso, Yoshimasa;
- Takada, Yoshihisa;
- Tomotsune, Ken;
- Chiba, Yasuko;
- Matsumura, Mihoko;
- Jojima, Teruo;
- Sato, Minoru;
- Fujita, Nobuya;
- Kuroda, Hisamoto;
- Murano, Shunichi;
- Usui, Isao
Publication type:
Article
Impact of dapagliflozin, an SGLT2 inhibitor, on serum levels of soluble dipeptidyl peptidase-4 in patients with type 2 diabetes and non-alcoholic fatty liver disease.
Published in:
2019
By:
- Aso, Yoshimasa;
- Kato, Kanako;
- Sakurai, Shintaro;
- Kishi, Haruka;
- Shimizu, Masanori;
- Jojima, Teruo;
- Iijima, Toshie;
- Maejima, Yuko;
- Shimomura, Kenju;
- Usui, Isao
Publication type:
journal article
Evaluation of the effects of dapagliflozin, a sodium‐glucose co‐transporter‐2 inhibitor, on hepatic steatosis and fibrosis using transient elastography in patients with type 2 diabetes and non‐alcoholic fatty liver disease.
Published in:
Diabetes, Obesity & Metabolism, 2019, v. 21, n. 2, p. 285, doi. 10.1111/dom.13520
By:
- Shimizu, Masanori;
- Suzuki, Kunihiro;
- Kato, Kanako;
- Jojima, Teruo;
- Iijima, Toshie;
- Murohisa, Toshimitsu;
- Iijima, Makoto;
- Takekawa, Hidehiro;
- Usui, Isao;
- Hiraishi, Hideyuki;
- Aso, Yoshimasa
Publication type:
Article
CD‐1db/db mice: A novel type 2 diabetic mouse model with progressive kidney fibrosis.
Published in:
Journal of Diabetes Investigation, 2020, v. 11, n. 6, p. 1470, doi. 10.1111/jdi.13311
By:
- Mizunuma, Yuiko;
- Kanasaki, Keizo;
- Nitta, Kyoko;
- Nakamura, Yuka;
- Ishigaki, Yasuhito;
- Takagaki, Yuta;
- Kitada, Munehiro;
- Li, Shaolan;
- Liu, Haijie;
- Li, Jinpeng;
- Usui, Isao;
- Aso, Yoshimasa;
- Koya, Daisuke
Publication type:
Article
Macrophage‐specific hypoxia‐inducible factor‐1α deletion suppresses the development of liver tumors in high‐fat diet‐fed obese and diabetic mice.
Published in:
Journal of Diabetes Investigation, 2019, v. 10, n. 6, p. 1411, doi. 10.1111/jdi.13047
By:
- Takikawa, Akiko;
- Usui, Isao;
- Fujisaka, Shiho;
- Tsuneyama, Koichi;
- Okabe, Keisuke;
- Nakagawa, Takashi;
- Nawaz, Allah;
- Kado, Tomonobu;
- Jojima, Teruo;
- Aso, Yoshimasa;
- Hayakawa, Yoshihiro;
- Yagi, Kunikimi;
- Tobe, Kazuyuki
Publication type:
Article
Hypertension and insulin resistance in adipose tissue.
Published in:
2023
By:
- Usui, Isao
Publication type:
Editorial
Common metabolic features of hypertension and type 2 diabetes.
Published in:
Hypertension Research, 2023, v. 46, n. 5, p. 1227, doi. 10.1038/s41440-023-01233-x
By:
- Usui, Isao
Publication type:
Article
Bofutsushosan improves gut barrier function with a bloom of Akkermansia muciniphila and improves glucose metabolism in mice with diet-induced obesity.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-62506-w
By:
- Fujisaka, Shiho;
- Usui, Isao;
- Nawaz, Allah;
- Igarashi, Yoshiko;
- Okabe, Keisuke;
- Furusawa, Yukihiro;
- Watanabe, Shiro;
- Yamamoto, Seiji;
- Sasahara, Masakiyo;
- Watanabe, Yoshiyuki;
- Nagai, Yoshinori;
- Yagi, Kunimasa;
- Nakagawa, Takashi;
- Tobe, Kazuyuki
Publication type:
Article
A case of hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome with a novel frameshift variant in GATA3, p.W10Cfs40, lacks kidney malformation.
Published in:
Clinical Case Reports, 2020, v. 8, n. 12, p. 2619, doi. 10.1002/ccr3.3186
By:
- Kishi, Haruka;
- Jojima, Teruo;
- Kogai, Takahiko;
- Iijima, Toshie;
- Ohira, Eriko;
- Tanuma, Dai;
- Konno, Sachiyo;
- Kato, Kanako;
- Kezuka, Atsumi;
- Akimoto, Kazumi;
- Sakumoto, Junko;
- Hishinuma, Akira;
- Tomaru, Takuya;
- Makita, Noriko;
- Usui, Isao;
- Aso, Yoshimasa
Publication type:
Article
Bullous pemphigoid associated with dipeptidyl peptidase‐4 inhibitor showing unfavorable outcomes despite immediate discontinuation of medication.
Published in:
Clinical Case Reports, 2020, v. 8, n. 10, p. 2007, doi. 10.1002/ccr3.3047
By:
- Shinohara, Yasutake;
- Iijima, Toshie;
- Sakurai, Shintaro;
- Jojima, Teruo;
- Ohira, Eriko;
- Hayashi, Shujiro;
- Usui, Isao;
- Igawa, Ken;
- Aso, Yoshimasa
Publication type:
Article
Effects of luseogliflozin on arterial properties in patients with type 2 diabetes mellitus: The multicenter, exploratory LUSCAR study.
Published in:
Journal of Clinical Hypertension, 2020, v. 22, n. 9, p. 1585, doi. 10.1111/jch.13988
By:
- Kario, Kazuomi;
- Okada, Kenta;
- Murata, Mitsunobu;
- Suzuki, Daisuke;
- Yamagiwa, Kayo;
- Abe, Yasuhisa;
- Usui, Isao;
- Tsuchiya, Norihiro;
- Iwashita, Chie;
- Harada, Noriko;
- Okawara, Yukie;
- Ishibashi, Shun;
- Hoshide, Satoshi
Publication type:
Article
Denosumab improves clinical manifestations of hypophosphatemic osteomalacia by adefovir-induced Fanconi syndrome: a case report.
Published in:
2019
By:
- Kunii, Tomohisa;
- Iijima, Toshie;
- Jojima, Teruo;
- Shimizu, Masanori;
- Kase, Masato;
- Sakurai, Shintaro;
- Kogai, Takahiko;
- Usui, Isao;
- Aso, Yoshimasa
Publication type:
journal article
FTO Gene Polymorphism Is Associated with Type 2 Diabetes through Its Effect on Increasing the Maximum BMI in Japanese Men.
Published in:
PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0165523
By:
- Kamura, Yutaka;
- Iwata, Minoru;
- Maeda, Shiro;
- Shinmura, Satomi;
- Koshimizu, Yukiko;
- Honoki, Hisae;
- Fukuda, Kazuhito;
- Ishiki, Manabu;
- Usui, Isao;
- Fukushima, Yasuo;
- Takano, Atsuko;
- Kato, Hiromi;
- Murakami, Shihou;
- Higuchi, Kiyohiro;
- Kobashi, Chikaaki;
- Tobe, Kazuyuki
Publication type:
Article
Efficacy of Low Dose of Rosuvastatin on Serum Lipid Profile in Japanese Type 2 Diabetic Patients.
Published in:
Diabetes, 2007, v. 56, p. A621
By:
- Urakaze, Masaharu;
- Kobashi, Chikaaki;
- Asamizu, Sachie;
- Din, Amal Khalifa Norel;
- Iwata, Minoru;
- Usui, Isao;
- Yamazaki, Katsuya;
- Kobayashi, Masashi
Publication type:
Article
The Increase of Visceral Fat Area Correlates with Macroangiopathy in Type 2 Diabetic Patients.
Published in:
Diabetes, 2007, v. 56, p. A595
By:
- Kobashi, Chikaaki;
- Urakaze, Masaharu;
- Gotoh, Rie;
- Hiratani, Kazuyuki;
- Norel Din, Amal Khalifa;
- Asamizu, Sachie;
- Kanatani, Yukiko;
- Iwata, Minoru;
- Uno, Tatsuhito;
- Ishiki, Manabu;
- Usui, Isao;
- Yamazaki, Katsuya;
- Kobayashi, Masashi
Publication type:
Article
Pitavastatin Reduces the Increase in MCP-1 Production from 3T3L1 Preadipocytes.
Published in:
Diabetes, 2007, v. 56, p. A507
By:
- Asamizu, Sachie;
- Urakaze, Masaharu;
- Kobashi, Chikaaki;
- Din, Amal Khalifa Norel;
- Fujisaka, Shiho;
- Kanatani, Yukiko;
- Bukahari, Agussalim;
- Suzuki, Hikari;
- Yamazaki, Yuh;
- Iwata, Minoru;
- Ishiki, Manabu;
- Usui, Isao;
- Yamazaki, Katsuya;
- Kobayashi, Masashi
Publication type:
Article
Telmisartan Improves Insulin Resistance by Increasing Apoptosis of Fat Cells and Decreasing Macrophage Infiltration in High Fat-fed Mice.
Published in:
Diabetes, 2007, v. 56, p. A453
By:
- Fujisaka, Shiho;
- Usui, Isao;
- Yamazaki, Yu;
- Bukhari, Agussalim;
- Kanatani, Yukiko;
- Suzuki, Hikari;
- He, Jianying;
- Ishiki, Manabu;
- Iwata, Minoru;
- Hiratani, Kazuyuki;
- Urakaze, Masaharu;
- Kobayashi, Masashi
Publication type:
Article
Effects of Pioglitazone on SOCS3 Expression: Potential Mechanisms for Its Effects on Insulin Sensitivity and Adiponectin Expression.
Published in:
Diabetes, 2007, v. 56, p. A356
By:
- Kanatani, Yukiko;
- Usui, Isao;
- Ishizuka, Ken;
- Fujisaka, Shiho;
- Bukhari, Agussalim;
- Jianying He;
- Yamazaki, Yu;
- Suzuki, Hikari;
- Iwata, Minoru;
- Ishiki, Manabu;
- Urakaze, Masaharu;
- Kobayashi, Masashi
Publication type:
Article
The Effect of Angiotensin Receptor Blockers or Thiazolidinediones on Inflammatory Cytokines in Diabetic State.
Published in:
Diabetes, 2007, v. 56, p. A351
By:
- Khalifa, Amal;
- Din, Norel;
- Urakaze, Masaharu;
- Kobashi, Chikaaki;
- Asamizu, Sachie;
- Fujisaka, Shiho;
- Kanatani, Yukiko;
- Bukahari, Agussalim;
- Suzuki, Hikari;
- Yamazaki, Yuh;
- Ishiki, Manabu;
- Iwata, Minoru;
- Usui, Isao;
- Yamazaki, Katsuya;
- Kobayashi, Masashi
Publication type:
Article
CaMKII-Alpha-Transgenic Mice Shows Pathological Changes of Diabetic Nephropathy with Enhanced Expression of PDGF B-Chain and PDGF Beta-Receptor.
Published in:
Diabetes, 2007, v. 56, p. A203
By:
- Suzuki, Hikari;
- Oya, Takeshi;
- Usui, Isao;
- Kato, Ichiro;
- Yamazaki, Yu;
- Fujisaka, Shiho;
- Bukhari, Agussalim;
- Asamizu, Sachie;
- Kanatani, Yukiko;
- Ishiki, Manabu;
- Urakaze, Masaharu;
- Takasawa, Shin;
- Okamoto, Hiroshi;
- Sasahara, Masakiyo;
- Kobayashi, Masashi
Publication type:
Article
Effects of pioglitazone on suppressor of cytokine signaling 3 expression: potential mechanisms for its effects on insulin sensitivity and adiponectin expression.
Published in:
2007
By:
- Kanatani Y;
- Usui I;
- Ishizuka K;
- Bukhari A;
- Fujisaka S;
- Urakaze M;
- Haruta T;
- Kishimoto T;
- Naka T;
- Kobayashi M;
- Kanatani, Yukiko;
- Usui, Isao;
- Ishizuka, Ken;
- Bukhari, Agussalim;
- Fujisaka, Shiho;
- Urakaze, Masaharu;
- Haruta, Tetsuro;
- Kishimoto, Tadamitsu;
- Naka, Tetsuji;
- Kobayashi, Masashi
Publication type:
journal article
Effects of Pioglitazone on Suppressor of Cytokine Signaling 3 Expression.
Published in:
Diabetes, 2007, v. 56, n. 3, p. 795, doi. 10.2337/db06-1039
By:
- Kanatani, Yukiko;
- Usui, Isao;
- Ishizuka, Ken;
- Bukhari, Agussalim;
- Fujisaka, Shiho;
- Urakaze, Masaharu;
- Haruta, Tetsuro;
- Kishimoto, Tadamitsu;
- Naka, Tetsuji;
- Kobayashi, Masashi
Publication type:
Article
Adenovirus-mediated adiponectin expression augments skeletal muscle insulin sensitivity in male Wistar rats.
Published in:
2005
By:
- Satoh, Hiroaki;
- Nguyen, M.T. Audrey;
- Trujillo, Maria;
- Imamura, Takeshi;
- Usui, Isao;
- Scherer, Philipp E.;
- Olefsky, Jerrold M.
Publication type:
journal article
Growth hormone induces cellular insulin resistance by uncoupling phosphatidylinositol 3-kinase and its downstream signals in 3T3-L1 adipocytes.
Published in:
2001
By:
- Takano, Atsuko;
- Haruta, Tetsuro;
- Iwata, Minoru;
- Usui, Isao;
- Uno, Tatsuhito;
- Kawahara, Junko;
- Ueno, Eiichi;
- Sasaoka, Toshiyasu;
- Kobayashi, Masashi;
- Takano, A;
- Haruta, T;
- Iwata, M;
- Usui, I;
- Uno, T;
- Kawahara, J;
- Ueno, E;
- Sasaoka, T;
- Kobayashi, M
Publication type:
journal article
Pioglitazone ameliorates tumor necrosis factor-alpha-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator--activated receptor-gamma.
Published in:
2001
By:
- Iwata, Minoru;
- Haruta, Tetsuro;
- Usui, Isao;
- Takata, Yasumitsu;
- Takano, Atsuko;
- Uno, Tatsuhito;
- Kawahara, Junko;
- Ueno, Eiichi;
- Sasaoka, Toshiyasu;
- Ishibashi, Osamu;
- Kobayashi, Masashi;
- Iwata, M;
- Haruta, T;
- Usui, I;
- Takata, Y;
- Takano, A;
- Uno, T;
- Kawahara, J;
- Ueno, E;
- Sasaoka, T
Publication type:
journal article
Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma.
Published in:
Respirology, 2013, v. 18, n. 2, p. 332, doi. 10.1111/j.1440-1843.2012.02284.x
By:
- ICHIKAWA, TOMOMI;
- HAYASHI, RYUJI;
- SUZUKI, KENSUKE;
- IMANISHI, SHINGO;
- KAMBARA, KENTA;
- OKAZAWA, SEISUKE;
- INOMATA, MINEHIKO;
- YAMADA, TORU;
- YAMAZAKI, YU;
- KOSHIMIZU, YUKIKO;
- MIWA, TOSHIRO;
- MATSUI, SHOKO;
- USUI, ISAO;
- URAKAZE, MASAHARU;
- MATSUYA, YUJI;
- SASAHARA, MASAKIYO;
- TOBE, KAZUYUKI
Publication type:
Article
Switching from the tablet to the powder formulation of levothyroxine corrects severe hypothyroidism in a patient with lactose intolerance.
Published in:
Endocrine Journal, 2022, v. 69, n. 8, p. 941, doi. 10.1507/endocrj.ej21-0656
By:
- Teruo Jojima;
- Toshimitsu Shinzawa;
- Eriko Ohira;
- Shintaro Sakurai;
- Takuya Tomara;
- Toshie Iyma;
- Takahiko Kogai;
- Isao Usui;
- Yoshimasa Aso
Publication type:
Article
Symptomatic hypocalcemia after treatment for hyperthyroidism in a woman with chromosome 22q11.2 deletion syndrome complicated by Graves' disease: longitudinal changes in the number of subsets of CD4 and CD8 lymphocytes after thyroidectomy.
Published in:
Endocrine Journal, 2021, v. 68, n. 10, p. 1187, doi. 10.1507/endocrj.ej20-0717
By:
- Toshie Iijima;
- Teruo Jojima;
- Soichiro Hosonuma;
- Eriko Ohhira;
- Takuya Tomaru;
- Takahiko Kogai;
- Isao Usui;
- Yoshimasa Aso
Publication type:
Article
Concurrent variant type 3 autoimmune polyglandular syndrome and pulmonary arterial hypertension in a Japanese woman.
Published in:
Endocrine Journal, 2018, v. 65, n. 4, p. 493, doi. 10.1507/endocrj.ej17-0465
By:
- Toshie Iijima;
- Takafumi Niitani;
- Seiichi Tanaka;
- Kazunori Yanagi;
- Teruo Jojima;
- Kunihiro Suzuki;
- Isao Usui;
- Yoshimasa Aso
Publication type:
Article
Partial depletion of CD206-positive M2-like macrophages induces proliferation of beige progenitors and enhances browning after cold stimulation.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-32803-6
By:
- Igarashi, Yoshiko;
- Nawaz, Allah;
- Kado, Tomonobu;
- Bilal, Muhammad;
- Kuwano, Takahide;
- Yamamoto, Seiji;
- Sasahara, Masakiyo;
- Jiuxiang, Xu;
- Inujima, Akiko;
- Koizumi, Keiichi;
- Imura, Johji;
- Shibahara, Naotoshi;
- Usui, Isao;
- Fujisaka, Shiho;
- Tobe, Kazuyuki
Publication type:
Article
Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2020, v. 11, n. 1, p. 241, doi. 10.1002/jcsm.12530
By:
- Nishida, Yasuhiro;
- Nawaz, Allah;
- Kado, Tomonobu;
- Takikawa, Akiko;
- Igarashi, Yoshiko;
- Onogi, Yasuhiro;
- Wada, Tsutomu;
- Sasaoka, Toshiyasu;
- Yamamoto, Seiji;
- Sasahara, Masakiyo;
- Imura, Johji;
- Tokuyama, Kumpei;
- Usui, Isao;
- Nakagawa, Takashi;
- Fujisaka, Shiho;
- Kunimasa, Yagi;
- Tobe, Kazuyuki
Publication type:
Article
Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age‐associated insulin resistance.
Published in:
Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12798
By:
- Gulshan, Maryam;
- Yaku, Keisuke;
- Okabe, Keisuke;
- Mahmood, Arshad;
- Sasaki, Tsutomu;
- Yamamoto, Masashi;
- Hikosaka, Keisuke;
- Usui, Isao;
- Kitamura, Tadahiro;
- Tobe, Kazuyuki;
- Nakagawa, Takashi
Publication type:
Article
Effects of treatment with methimazole on circulating CD4+ and CD8+ T cells positive for programed cell death protein‐1 and on subsets of CD4+ T cells in untreated hyperthyroid patients with Graves' disease.
Published in:
Clinical Endocrinology, 2022, v. 97, n. 6, p. 841, doi. 10.1111/cen.14788
By:
- Hirao, Nanako;
- Iijima, Toshie;
- Tanuma, Dai;
- Ohira, Eriko;
- Kurai, Hidetaka;
- Shinzawa, Toshimitsu;
- Kase, Masato;
- Sakurai, Shintaro;
- Tomaru, Takuya;
- Jojima, Teruo;
- Usui, Isao;
- Aso, Yoshimasa
Publication type:
Article
Astaxanthin, a Marine Carotenoid, Maintains the Tolerance and Integrity of Adipose Tissue and Contributes to Its Healthy Functions.
Published in:
Nutrients, 2021, v. 13, n. 12, p. 4374, doi. 10.3390/nu13124374
By:
- Nawaz, Allah;
- Nishida, Yasuhiro;
- Takikawa, Akiko;
- Fujisaka, Shiho;
- Kado, Tomonobu;
- Aminuddin, Aminuddin;
- Bilal, Muhammad;
- Jeelani, Ishtiaq;
- Aslam, Muhammad Rahil;
- Nishimura, Ayumi;
- Kuwano, Takahide;
- Watanabe, Yoshiyuki;
- Igarashi, Yoshiko;
- Okabe, Keisuke;
- Ahmed, Saeed;
- Manzoor, Azhar;
- Usui, Isao;
- Yagi, Kunimasa;
- Nakagawa, Takashi;
- Tobe, Kazuyuki
Publication type:
Article
Ratio of low molecular weight serum adiponectin to the total adiponectin value is associated with type 2 diabetes through its relation to increasing insulin resistance.
Published in:
PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0192609
By:
- Iwata, Minoru;
- Hara, Kazuo;
- Kamura, Yutaka;
- Honoki, Hisae;
- Fujisaka, Shiho;
- Ishiki, Manabu;
- Usui, Isao;
- Yagi, Kunimasa;
- Fukushima, Yasuo;
- Takano, Atsuko;
- Kato, Hiromi;
- Murakami, Shihou;
- Higuchi, Kiyohiro;
- Kobashi, Chikaaki;
- Fukuda, Kazuhito;
- Koshimizu, Yukiko;
- Tobe, Kazuyuki
Publication type:
Article
1150-P: Empagliflozin Decreases the Plasma Concentration of Plasminogen Activator Inhibitor-1 (PAI-1) in Patients with Type 2 Diabetes: Association with Improvement of Fibrinolysis.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1150-P
By:
- NIITANI, TAKAFUMI;
- SAKURAI, SHINTARO;
- JOJIMA, TERUO;
- IIJIMA, TOSHIE;
- TOMARU, TAKUYA;
- USUI, ISAO;
- ASO, YOSHIMASA
Publication type:
Article
2186-PUB: Comparison of Insulin Degludec (IDeg)/Insulin Aspart (IAsp) Coformulation Therapy Twice Daily with Free Combination of GLP-1 Receptor Agonist Liraglutide plus Insulin Degludec in Tochigi: IDEAL Trial.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2186-PUB
By:
- ASO, YOSHIMASA;
- JOJIMA, TERUO;
- SAKURAI, SHINTARO;
- IIJIMA, TOSHIE;
- TOMARU, TAKUYA;
- USUI, ISAO
Publication type:
Article
132-OR: Effects of Dapagliflozin, an SGLT2 Inhibitor, on Hepatic Steatosis and Fibrosis Evaluated by Transient Elastography in Patients with Type 2 Diabetes and Nonalcoholic Fatty Liver Disease.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-132-OR
By:
- ASO, YOSHIMASA;
- JOJIMA, TERUO;
- IIJIMA, TOSHIE;
- USUI, ISAO
Publication type:
Article
1229-P: Dapagliflozin Improves Liver Dysfunction in Parallel with a Decrease in Serum Soluble DPP-4/CD26 Level in Type 2 Diabetic Patients with Nonalcoholic Fatty Liver Disease.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1229-P
By:
- KATO, KANAKO;
- ASO, YOSHIMASA;
- JOJIMA, TERUO;
- IIJIMA, TOSHIE;
- USUI, ISAO
Publication type:
Article
1987-P: Nampt Deletion Changes Metabolism in Adipose Tissue and Prevents Diet-Induced Obesity.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1987-P
By:
- OKABE, KEISUKE;
- NAWAZ, ALLAH;
- FUJISAKA, SHIHO;
- YAGI, KUNIMASA;
- KADO, TOMONOBU;
- USUI, ISAO;
- NAKAGAWA, TAKASHI;
- TOBE, KAZUYUKI
Publication type:
Article
The Radioprotective 105/MD-1 Complex Contributes to Diet-Induced Obesity and Adipose Tissue Inflammation.
Published in:
Diabetes, 2012, v. 61, n. 5, p. 1199, doi. 10.2337/db11-1182
By:
- Watanabe, Yasuharu;
- Nakamura, Tomoya;
- Ishikawa, Sho;
- Fujisaka, Shiho;
- Usui, Isao;
- Tsuneyama, Koichi;
- Ichihara, Yoshinori;
- Wada, Tsutomu;
- Hirata, Yoichiro;
- Suganami, Takayoshi;
- Izaki, Hirofumi;
- Akira, Shizuo;
- Miyake, Kensuke;
- Kanayama, Hiro-omi;
- Shimabukuro, Michio;
- Sata, Masataka;
- Sasaoka, Toshiyasu;
- Ogawa, Yoshihiro;
- Tobe, Kazuyuki;
- Takatsu, Kiyoshi
Publication type:
Article
Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice.
Published in:
Diabetes, 2009, v. 58, n. 11, p. 2574, doi. 10.2337/db08-1475
By:
- Fujisaka, Shiho;
- Usui, Isao;
- Bukhari, Agussalim;
- Ikutani, Masashi;
- Oya, Takeshi;
- Kanatani, Yukiko;
- Tsuneyama, Koichi;
- Nagai, Yoshinori;
- Takatsu, Kiyoshi;
- Urakaze, Masaharu;
- Kobayashi, Masashi;
- Tobe, Kazuyuki
Publication type:
Article

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