We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Elucidation of the Conformation of Polyglycine Organo-Polyoxotungstates: Evidence for Zipper Folding.
- Authors
Vilona, Debora; Lachkar, David; Dumont, Elise; Lelli, Moreno; Lacôte, Emmanuel
- Abstract
The conformation of a family of α1 and α2 polyglycine-containing organo-polyoxometalates was determined through a mixed experimental/molecular dynamics approach. The flexible peptide arm folds around the metal oxide surface in a rigid arrangement in low to average polarity solvents. The topology of the hybrid is the main factor that determines which oxos from the metal-oxide surface accept a H-bond from the closest amino acid. The rest of the peptide follows in a zipper mechanism that establishes a H-bond network that locks the system. The covalent constraint leads to a new type of H-bond where two consecutive amino acids clamp down terminal oxo ligands.
- Subjects
POLYOXOTUNGSTATES; METALLIC oxides; AMINO acids; HYDROGEN bonding; POLYOXOMETALATES
- Publication
Chemistry - A European Journal, 2017, Vol 23, Issue 54, p13323
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.201703509