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- Title
Age-dependence of lipid parameters in the general population and vegetarians.
- Authors
V. Richter; F. Rassoul; B. Hentschel; K. Kothe; M. Krobara; R. Unger; K. Purschwitz; W. Rotzsch; J. Thiery; K. Muradian
- Abstract
Summary. Age-dependent changes of lipid metabolism may arise both as a result of mechanisms of biological ageing and factors influencing age-dependent changes. To study possible influences of nutrition and life-style of vegetarians on age-dependence of lipid parameters, subjects of general population were compared with vegetarians. In the frame of population-based lipid screening projects in the city of Leipzig/Germany (Lipid Study Leipzig, LSL) 10 550 subjects (3 816 men and 6 734 women, age 18–99 years) of general population were compared with 417 vegetarians (vegans, lacto-vegetarians, lacto-ovo-vegetarians, 148 men and 269 women, age 18–93 years). Most of the vegetarians included in the study were members of the German Society of Vegetarians. The study program included capillary blood cholesterol measurements and the determination of high-density lipoprotein (HDL)-cholesterol, the measurement of other cardiovascular risk factors and the evaluation of dietary and life-style factors. Evaluation of cardiovascular risk profile within LSL was connected with individual consultation. The mean total cholesterol and non-HDL-cholesterol level and the total: HDL-cholesterol ratio showed the expected age-dependence, with maximum values within the decade 60–70 years. Vegetarians showed lower total and non-HDL-cholesterol levels in comparison with the general population. Furthermore, the age-dependent increase of these parameters is less pronounced under the conditions of vegetarian nutrition and life-style. Especially in young adulthood a significant difference is observed. Thus, the results of the present study reveal the role of nutritional and life-style factors that determine the lipid profile on a population basis and suggest that the known age-dependent rise of the level of atherogenic plasma lipoproteins is partly preventable.
- Subjects
AGING; CHOLESTEROL; LIFESTYLES; LIPOPROTEINS; NUTRITION; BIOLOGY; PHYSIOLOGY; HEALTH; HEALTH status indicators; WELL-being
- Publication
Zeitschrift für Gerontologie und Geriatrie, 2004, Vol 37, Issue 3, p207
- ISSN
0948-6704
- Publication type
Article
- DOI
10.1007/s00391-004-0232-3