The new cytisine derivatives N-(3′- β-bromoethoxy-4′-methoxy-2′-bromobenzyl)cytisine and N-[2′-bromo-4′-methoxy-3′-( β-cytisinylethoxy)benzyl]cytisine were prepared from cytisine, substituted benzaldehyde, and dibromoethane. The structures of the synthesized compounds were established using IR, mass, and PMR spectral data.