We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Increased interleukin-1 and interleukin-1 receptor antagonist levels in cervical mucus in the ovulatory phase in comparison with the follicular phase.
- Authors
Kanai, T; Fukuda-Miki, M; Shimoya, K; Azuma, C; Hashimoto, K; Nobunaga, T; Tokugawa, Y; Tsujimoto, M; Saji, F; Murata, Y
- Abstract
Interleukin-1 (IL-1) receptor antagonist (IL-1ra) levels in the cervical mucus of women in the ovulatory phase are significantly higher than those in the follicular phase. IL-1 titers of women in the ovulatory phase are also significantly higher than those in the follicular phase. A positive correlation between IL-1ra and IL-1 levels in the cervical mucus was observed. Immunohistochemistry using an anti-IL-1ra monoclonal antibody revealed positive staining in the epithelial cells of the endocervix. These results suggest that IL-1ra from cervical epithelial cells protects the reproductive system from the toxicity of IL-1 produced in the endocervix.
- Publication
Gynecologic & Obstetric Investigation, 1997, Vol 43, Issue 3, p166
- ISSN
0378-7346
- Publication type
journal article