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- Title
A avaliação mecanística teórica da utilização de oxihidróxido de cobalto (III) em sensores eletroquímicos de tramadol.
- Authors
Tkach, Volodymyr V.; Ivanushko, Yana G.; de Oliveira, Sílvio C.; Ojani, Reza; Yagodynets, Petró I.
- Abstract
The possibility of tramadol in vivo and in vitro electrochemical determination by means of the sensor, based on cobalt (III) oxyhydroxide and its composite with conducting polymers was evaluated from the mechanistic point of view. The mathematical model, correspondent to the suggested mechanism, was developed and analyzed by means of linear stability theory and bifurcation analysis. It was shown that CoO(OH) may be applied to the tramadol electrochemical determination in neutral and lightly alkaline pH values, correspondent to the more efficient oxidation of the compound. The possibility of oscillatory and monotonic instabilities has also been modified.
- Publication
Revista Colombiana de Ciencias Químico-Farmacéuticas, 2017, Vol 46, Issue 2, p188
- ISSN
0034-7418
- Publication type
Article
- DOI
10.15446/rcciquifa.v46n2.67955