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- Title
前列地尔与缬沙坦联合治疗肾小球肾炎的疗效观察.
- Authors
李名波; 孙智梅; 任卓琴; 董平定
- Abstract
OBJECTIVE:To probe into the clinical efficacy of alprostadil combined with valsartan in treatment of patients with glomerulonephritis .METHODS: 88 patients with glomerulonephritis admitted into Qianjiang Central Hospital from Aug.2014 to Feb.2016 were selected to be divided into observation group and control group via the random number table, with 44 cases in each .The control group were treated with valsartan, while the observation group additionally received alprostadil based on the control group .The treatment effects and changes of indicators of renal function of two groups were observed .RESULTS: The total effective rate of observation group was 93.18% ( 41/44 ), significantly higher than that of control group [72.73%(32/44)], with statistically significant difference (P<0.05). After treatment, the microalbuminuria, serum creatinine, urea nitrogen level of two groups were better than that of before treatment;and the observation group was better than that of control group ;with statistically significant difference ( P<0.05).CONCLUSIONS:Alprostadil combined with valsartan in treatment of patients with glomerulonephritis can help to improve the renal function of patients with a significant effect .
- Publication
Evaluation & Analysis of Drug-Use in Hospitals of China, 2016, Vol 16, Issue 11, p1494
- ISSN
1672-2124
- Publication type
Article
- DOI
10.14009/j.issn.1672-2124.2016.11.018