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- Title
Innate‐like T Cells: Connecting the Dots Linking Microscopic Intestinal Inflammation to Spondyloarthritis.
- Authors
Zhao, Meng; Kronenberg, Mitchell
- Abstract
The article discusses spondyloarthritis (SpA), a group of inflammatory rheumatic conditions affecting the spine and joints, specifically focusing on nonradiographic axial SpA with gut inflammation. It explores the role of innate-like T cells, such as γδT cells, mucosal-associated invariant T (MAIT) cells, and invariant natural killer T (iNKT) cells, in SpA pathogenesis, highlighting their potential importance in producing IL-17, a cytokine relevant to SpA.
- Subjects
DISEASE progression; INTERLEUKINS; INFLAMMATION; ANKYLOSIS; SPONDYLOARTHROPATHIES; INTESTINAL diseases; T cells
- Publication
Arthritis & Rheumatology, 2023, Vol 75, Issue 11, p1907
- ISSN
2326-5191
- Publication type
Article
- DOI
10.1002/art.42660