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- Title
Right Atrial Size Relates to Right Ventricular End-Diastolic Pressure in an Adult Population with Congenital Heart Disease.
- Authors
Do, Doan Hoa; Therrien, Judith; Marelli, Ariane; Martucci, Giuseppe; Afilalo, Jonathan; Sebag, Igal A.
- Abstract
Aim: Noninvasive markers of right ventricular (RV) diastolic dysfunction are limited by their lack of reproducibility and accuracy. We tested the hypothesis that right atrial (RA) size measured by echocardiography was correlated to invasive parameters of RV diastolic filling. Methods and Results: We studied 31 consecutive adult patients with congenital heart disease. From 2D echocardiography images, we measured maximal RA long-axis and short-axis lengths, area and volume. We compared each of these measures to right ventricular end-diastolic pressure (RVEDP) and mean right atrial pressure (mRAP) measured by right heart catheterization. RA long-axis, short-axis, area, and volume correlated significantly with RVEDP (r = 0.78, P < 0.001; r = 0.61, P < 0.001; r = 0.79, P < 0.001; and r = 0.75, P < 0.001, respectively) and mRAP (r = 0.66, P < 0.001; r = 0.56, P = 0.002; r = 0.70, P < 0.001; r = 0.68, P < 0.001, respectively). Single cut points for each echocardiographic parameter demonstrated reasonable accuracy to rule-in and rule-out RVEDP ≥7 mm Hg (sensitivity = 74%, specificity = 82%, positive LR = 4.1, negative LR = 0.32 for RA long-axis of 49 mm; sensitivity = 89%, specificity = 82%, positive LR = 4.9, negative LR = 0.12 for RA area of 14 cm; sensitivity = 89%, specificity = 82%, positive LR = 4.9, negative LR = 0.13 for RA volume of 37 mL). Conclusion: RA size measured by echocardiography is strongly correlated to invasive parameters of RV diastolic filling and predicts high RV end-diastolic pressure. (Echocardiography 2011;28:109-116)
- Subjects
ANALYSIS of variance; BLOOD pressure; CARDIAC catheterization; COMPUTER software; CONFIDENCE intervals; CONGENITAL heart disease; RIGHT heart ventricle; HEART atrium; MAGNETIC resonance imaging; PROBABILITY theory; STATISTICS; DATA analysis; RETROSPECTIVE studies; RECEIVER operating characteristic curves
- Publication
Echocardiography, 2011, Vol 28, Issue 1, p109
- ISSN
0742-2822
- Publication type
Article
- DOI
10.1111/j.1540-8175.2010.01277.x