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- Title
Micro CT and Human Histological Analysis of a Peri-Implant Osseous Defect Grafted with Porous Titanium Granules: A Case Report.
- Authors
Wohlfahrt, Johan Caspar; Aass, Anne Merete; Rønold, Hans Jacob; Lyngstadaas, Ståle Petter
- Abstract
Treatment of peri-implant osseous defects represents a significant challenge for clinicians, and the need to evolve within predictable surgical procedures is important. This case report describes the surgical treatment and grafting with porous titanium granules (PTG) of one patient with a periimplant osseous defect. The suggested thrombogenic properties of titanium are intriguing from the perspective of osseous reconstructive surgery. In an ongoing randomized clinical trial using PTG for treatment of peri-implant osseous defects, one patient with one test implant was excluded and scheduled for implant removal. The surgical therapy included open flap debridement with surface decontamination with 24% EDTA gel, grafting with PTG, and resubmersion of the implant. After 12 months of healing, the implant with surrounding tissues was excised en bloc and micro CT and histological analyses were performed. Analyses showed PTG in close contact with new bone and with bone growing both into the porosities of the graft material and onto the adjacent implant surface. Element analysis demonstrated calcium and phosphorus in the new tissue embedding the PTG and the implant.
- Subjects
BONE substitutes; HISTOLOGICAL techniques; HOMOGRAFTS; HEALTH outcome assessment; TITANIUM; TREATMENT effectiveness
- Publication
International Journal of Oral & Maxillofacial Implants, 2011, Vol 26, Issue 1, pe9
- ISSN
0882-2786
- Publication type
Article