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- Title
Cure with ledipasvir/sofosbuvir for chronic hepatitis C virus in an individual with gastric bypass.
- Authors
Johnson, S. W.; Teachey, A. L.; Valanejad, S. M.; Griffin, S. M.; Weber, S. F.
- Abstract
What is known and objective The impact of gastric bypass surgery on the pharmacokinetics of various medications has been reported. Presently, no data exist for the treatment of chronic hepatitis C virus with ledipasvir/sofosbuvir ( LDV/ SOF) in an individual with a history of gastric bypass. Case description We report the successful cure of an individual who was treated with LDV/ SOF who had a history of gastric bypass. The patient tolerated LDV/ SOF well while only experiencing a minor headache. What is new and conclusion Ledipasvir/sofosbuvir treatment may still be effective in those with a history of gastric bypass surgery.
- Subjects
ANTIVIRAL agents; COMBINATION drug therapy; VIRAL load; GASTRIC bypass; TREATMENT effectiveness; CHRONIC hepatitis C; PHARMACODYNAMICS
- Publication
Journal of Clinical Pharmacy & Therapeutics, 2017, Vol 42, Issue 5, p624
- ISSN
0269-4727
- Publication type
Article
- DOI
10.1111/jcpt.12547