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- Title
Blood Simple.
- Authors
Stephenson, Joan
- Abstract
This article reports on the finding of bacterial enzymes that can be used to convert types A, B and AB blood into universal donor type O blood. The screening of fungal and bacterial isolates by researchers uncovered 2 gene families that encode enzymes capable of efficiently removing A and B antigens from red blood cells under conditions that preserve the cells' integrity and function. If proven safe in clinical trials, the discovery could help alleviate the shortages of type O blood which would not only improve the blood supply but enhance the safety of clinical transfusions.
- Subjects
DIRECTED blood donations; BLOOD collection; BLOOD transfusion; ENZYMES; GENES; ANTIGENS; ERYTHROCYTES; MEDICAL research
- Publication
JAMA: Journal of the American Medical Association, 2007, Vol 297, Issue 19, p2069
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.297.19.2069-b