We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
One‐pot synthesis of 1,8-dioxo-decahydroacridine and hexahydroquinoline derivatives catalyzed by a new natural deep eutectic mixture.
- Authors
Rahro, Parissa Naddaf; Shirini, Farhad
- Abstract
In this work, a novel natural deep eutectic mixture was prepared from glucose, pregabalin and urea and identified using a variety of techniques including Fourier transform infrared spectroscopy, thermogravimetric analysis, derivative thermogravimetry, differential thermal analysis and refractive index measurements. After the characterization the promoting ability of this reagent was studied in the synthesis of 1,8-dioxo-decahydroacridine and hexahydroquinoline derivatives through the one-pot Hantzsch condensation. Easy preparation of the reagent, green process, simple work-up procedure, high yields, and short reaction times are among the most important advantages of the reported protocol. In this research also, the antibacterial activities of the prepared deep eutectic mixture and some of the prepared products were studied against the Bacillus subtilis (Gram-positive) and Escherichia coli (Gram-negative) by the agar well diffusion method.
- Subjects
FOURIER transform infrared spectroscopy techniques; DIFFERENTIAL thermal analysis
- Publication
Research on Chemical Intermediates, 2023, Vol 49, Issue 11, p4879
- ISSN
0922-6168
- Publication type
Article
- DOI
10.1007/s11164-023-05125-0