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- Title
Metabolic syndrome and risk for ED: a meta-analysis.
- Authors
Liu, L H; Zhang, T; Zhang, Y R; Liu, T S; Zhang, H B; Chen, F Z; He, S H; Wei, A Y
- Abstract
There are many recent observational studies on metabolic syndrome (MS) and the risk for ED, and it is still inconclusive whether MS increases the risk for ED. This meta-analysis aims to detect a relationship between MS and ED. We identified eligible studies by searching PubMed, Embase and the Cochrane Library for articles published before August 2013. Adjusted relative risks (RR) with 95% confidence interval (CI) were calculated using random-effects or fixed-effects models. A total of 10 studies involving 4092 participants were included in the meta-analysis. MS was associated with an increased incidence of ED (RR=1.60, 95% CI=1.27-2.02, P<0.001), with significant evidence of heterogeneity among these studies (P for heterogeneity <0.001, I2=92.9%). The subgroup and sensitivity analyses confirmed the stability of the results and no publication bias was detected. The present meta-analysis suggests that MS is significantly associated with the risk for ED. Large-scale and well-designed prospective studies are required to further investigate the association between MS and risk for ED.
- Subjects
METABOLIC syndrome; META-analysis; SENSITIVITY analysis; HETEROGENEITY; CONFIDENCE intervals
- Publication
International Journal of Impotence Research, 2014, Vol 26, Issue 5, p196
- ISSN
0955-9930
- Publication type
Article
- DOI
10.1038/ijir.2014.3