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- Title
Synthesis And Antibacterial Activity of 1-Monolaurin.
- Authors
NITBANI, FEBRI ODEL; JUMINA; SISWANTA, DWI; SHOLIKHAH, ETI NURWENING; FITRIASTUTI, DHINA
- Abstract
An improvement of method for synthesizing 1-monolaurin from lauric acid and glycerol has been done. The reaction was carried on mol ratio between lauric acid and glycerol 1:1 at 130 °C for 6 h with variation of pTSA catalyst of 2.5%, 5%, 7.5% (w/w of lauric acid). The purification of 1-monolaurin was conducted only by extracting with alcoholic solution. The product of 1-monolaurin was obtained as a white solid with 100% of purity from variation of 2.5% and 5% of pTSA catalyst with 43.54% and 27.89% yield, respectively. 1-Monolaurin could inhibit the growth of S. aureus and E. coli bacteria at 500 µg/mL of concentration.
- Subjects
CATALYTIC activity; MONOLAURIN; LAURIC acid; GLYCERIN; CHEMICAL reactions
- Publication
Oriental Journal of Chemistry, 2018, Vol 34, Issue 2, p863
- ISSN
0970-020X
- Publication type
Article
- DOI
10.13005/ojc/340233