We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Comprehensive Assessment of Multibacillary Leprosy: A Prospective Study at a Tertiary Care Center in Chennai.
- Authors
Nithyalakshmi, R. S.; Dhanaselvi; Swaminathan, Thamizhselvi; Sampath, V.
- Abstract
Background: Leprosy remains a significant public health concern in many regions, including India, with multibacillary forms posing unique challenges in diagnosis and management. This study aimed to comprehensively assess the spectrum of disease in multibacillary leprosy patients at a tertiary care center in Chennai. Methods: A prospective study was conducted over one and a half years, involving 38 newly diagnosed and untreated multibacillary leprosy patients. Clinical, bacteriological, and treatment response parameters were evaluated using standardized methods. Statistical analysis was performed using SPSS version 26. Results: The study analyzed 38 multibacillary leprosy patients. The study cohort exhibited a mean age of 40.2 years, with a notable male predominance (79%) aged 30-39. Coolies (28.9%) were the most affected occupation group. Borderline lepromatous leprosy (66%) was prevalent. Clinical assessments showed trophic ulcers (13%) and grade 2 deformities like claw hand (5.3%) and lagophthalmos (2.6%). Bacteriological evaluation post-MDT revealed significant BI reduction at 6 months (p < 0.001). While most patients attained negative smears, some remained positive at 12 months, warranting continued surveillance for sustained clearance. Conclusion: This study provides comprehensive insights into the epidemiological, clinical, and bacteriological characteristics of multibacillary leprosy, highlighting the efficacy of multidrug therapy in achieving favorable treatment outcomes.
- Subjects
CHENNAI (India); INDIA; HANSEN'S disease; TERTIARY care; LONGITUDINAL method; PUBLIC health; PRESSURE ulcers; SEARCH warrants (Law)
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2024, Vol 15, Issue 3, p184
- ISSN
0975-3583
- Publication type
Article