Found: 31
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Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers.
- Published in:
- 2017
- By:
- Publication type:
- journal article
CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-35880-y
- By:
- Publication type:
- Article
Co-regulation and function of FOXM1/ RHNO1 bidirectional genes in cancer.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.55070
- By:
- Publication type:
- Article
A phosphorylation-and-ubiquitylation circuitry driving ATR activation and homologous recombination.
- Published in:
- Nucleic Acids Research, 2017, v. 45, n. 15, p. 8859, doi. 10.1093/nar/gkx571
- By:
- Publication type:
- Article
BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26227-6
- By:
- Publication type:
- Article
An extended APOBEC3A mutation signature in cancer.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21891-0
- By:
- Publication type:
- Article
Regulation of DNA break repair by transcription and RNA.
- Published in:
- SCIENCE CHINA Life Sciences, 2017, v. 60, n. 10, p. 1081, doi. 10.1007/s11427-017-9164-1
- By:
- Publication type:
- Article
The 2015 Albert Lasker Basic Medical Research Award: An exhilarating journey to the DNA damage checkpoint.
- Published in:
- SCIENCE CHINA Life Sciences, 2016, v. 59, n. 1, p. 103, doi. 10.1007/s11427-015-4984-3
- By:
- Publication type:
- Article
Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45693-2
- By:
- Publication type:
- Article
The RNA m5C modification in R-loops as an off switch of Alt-NHEJ.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41790-w
- By:
- Publication type:
- Article
An ATR-PrimPol pathway confers tolerance to oncogenic KRAS-induced and heterochromatin-associated replication stress.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40578-2
- By:
- Publication type:
- Article
Inhibition of ATR-Chk1 signaling blocks DNA double-strand-break repair and induces cytoplasmic vacuolization in metastatic osteosarcoma.
- Published in:
- Therapeutic Advances in Medical Oncology, 2020, v. 12, p. 1, doi. 10.1177/1758835920956900
- By:
- Publication type:
- Article
ATR-p53 Restricts Homologous Recombination in Response to Replicative Stress but Does Not Limit DNA Interstrand Crosslink Repair in Lung Cancer Cells.
- Published in:
- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023053
- By:
- Publication type:
- Article
Sensing, signaling, and responding to DNA damage: Organization of the checkpoint pathways in mammalian cells.
- Published in:
- Journal of Cellular Biochemistry, 2005, v. 94, n. 2, p. 298, doi. 10.1002/jcb.20355
- By:
- Publication type:
- Article
Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10993-5
- By:
- Publication type:
- Article
Using electrophoresis to observe the interaction of nitrogenase with ions.
- Published in:
- Electrophoresis, 2000, v. 21, n. 14, p. 2932, doi. 10.1002/1522-2683(20000801)21:14<2932::AID-ELPS2932>3.0.CO;2-I
- By:
- Publication type:
- Article
TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA.
- Published in:
- Nature, 2011, v. 471, n. 7339, p. 532, doi. 10.1038/nature09772
- By:
- Publication type:
- Article
DNA repair: A protein giant in its entirety.
- Published in:
- Nature, 2010, v. 467, n. 7316, p. 667, doi. 10.1038/467667a
- By:
- Publication type:
- Article
RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response.
- Published in:
- Cell Research, 2015, v. 25, n. 1, p. 9, doi. 10.1038/cr.2014.147
- By:
- Publication type:
- Article
Curcumin suppresses multiple DNA damage response pathways and has potency as a sensitizer to PARP inhibitor.
- Published in:
- Carcinogenesis, 2013, v. 34, n. 11, p. 2486, doi. 10.1093/carcin/bgt240
- By:
- Publication type:
- Article
SCF<sup>β-TRCP</sup> promotes cell growth by targeting PR-Set7/Set8 for degradation.
- Published in:
- Nature Communications, 2015, v. 6, n. 12, p. 10185, doi. 10.1038/ncomms10185
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- Publication type:
- Article
Targeting the DNA replication stress phenotype of KRAS mutant cancer cells.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83142-y
- By:
- Publication type:
- Article
A RAD18–UBC13–PALB2–RNF168 axis mediates replication fork recovery in BRCA1-deficient cancer cells.
- Published in:
- Nucleic Acids Research, 2024, v. 52, n. 15, p. 8861, doi. 10.1093/nar/gkae563
- By:
- Publication type:
- Article
An R-loop-initiated CSB–RAD52–POLD3 pathway suppresses ROS-induced telomeric DNA breaks.
- Published in:
- Nucleic Acids Research, 2020, v. 48, n. 3, p. 1285, doi. 10.1093/nar/gkz1114
- By:
- Publication type:
- Article
ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06586-3
- By:
- Publication type:
- Article
MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01180-5
- By:
- Publication type:
- Article
Analysis of DNA Damage Response Gene Alterations and Tumor Mutational Burden Across 17,486 Tubular Gastrointestinal Carcinomas: Implications for Therapy.
- Published in:
- Oncologist, 2019, v. 24, n. 10, p. 1340, doi. 10.1634/theoncologist.2019-0034
- By:
- Publication type:
- Article
Alternative lengthening of telomeres: from molecular mechanisms to therapeutic outlooks.
- Published in:
- Cell & Bioscience, 2020, v. 10, n. 1, p. 1, doi. 10.1186/s13578-020-00391-6
- By:
- Publication type:
- Article
Interaction with magnesium and ADP stabilizes both components of nitrogenase from Klebsiella pneumoniae against urea denaturation.
- Published in:
- Protein Science: A Publication of the Protein Society, 2000, v. 9, n. 1, p. 121
- By:
- Publication type:
- Article
Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16802-8
- By:
- Publication type:
- Article
m5C modification of mRNA serves a DNA damage code to promote homologous recombination.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16722-7
- By:
- Publication type:
- Article