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- Title
Clinical Implications of Accurate Subtyping of Pituitary Adenomas: Perspectives from the Treating Physician.
- Authors
GOMEZ-HERNANDEZ, Karen; EZZAT, Shereen; ASA, Sylvia L.; METE, Özgür
- Abstract
Pituitary adenomas comprise a heterogenous group of adenohypophyseal tumours with distinct clinicopathological features across both the clinically functioning and silent groups. although, predicting a clinically aggressive course remains challenging, accurate subtyping of pituitary adenomas offers valuable prognostic information that together with other clinical and radiological information serves as a platform for tailored treatment and follow-up. For instance, silent subtype 3 pituitary adenomas, silent corticotroph adenomas, acidophil stem cell adenomas, Crooke cell adenomas, and sparsely granulated somatotroph adenomas show more invasive growth. This review has been formulated as a set of practical questions that address the distinct clinical behaviour of a selected group of pituitary adenoma subtypes.
- Subjects
ADENOMA; PITUITARY tumors; PITUITARY cancer; HYPERTHYROIDISM; CUSHING'S syndrome; ACROMEGALY
- Publication
Turkish Journal of Pathology, 2015, Vol 31, p4
- ISSN
1018-5615
- Publication type
Article
- DOI
10.5146/tjpath.2015.01311