We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Hypoglobulinemia in a dog with disseminated plasma cell neoplasia: Case report and review of the diagnostic criteria.
- Authors
Brown, Juliet E.; Russell, Elise B.; Moore, A. Russell; Oscos‐Snowball, Astrid; Stent, Andrew; Courtman, Natalie F.
- Abstract
This is the first reported case of hypoglobulinemia in a dog with disseminated plasma cell neoplasia. A 6‐year‐old male intact Rottweiler was referred to the U‐Vet Animal Hospital (Werribee, Vic, Australia) for weight loss, hyporexia, lethargy, vomiting, and soft stools. Examination of a buffy coat preparation and splenic and liver aspirates revealed a monomorphic population of plasmacytoid cells, and the same cells comprised approximately 90% of bone marrow samples submitted for cytologic and histologic evaluation. Biochemistry revealed a hypoglobulinemia, and the presence of an M‐protein was not supported by serum and urine protein electrophoresis or serum immunofixation. Immunohistochemistry demonstrated strong nuclear labeling for MUM‐1.
- Subjects
PLASMA cells; BLOOD protein electrophoresis; BONE marrow; CELL populations; DOGS
- Publication
Veterinary Clinical Pathology, 2021, Vol 50, Issue 2, p227
- ISSN
0275-6382
- Publication type
Article
- DOI
10.1111/vcp.12948