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- Title
A global map of human gene expression.
- Authors
Lukk, Margus; Kapushesky, Misha; Nikkilä, Janne; Parkinson, Helen; Goncalves, Angela; Huber, Wolfgang; Ukkonen, Esko; Brazma, Alvis
- Abstract
A letter is presented which described the construction of a global map of human gene expression from a large microarray data set in 2010. The collection and extraction of 9,000 raw data files from the public databases Gene Expression Omnibus and ArrayExpress is described. It details the application of an online query interface to explore the generated data. Data interpretation using principal component analysis, hierarchical clustering and one-way analysis of variance are detailed.
- Subjects
RESEARCH; HUMAN gene mapping; GENE mapping; GENE expression; DNA microarrays; AMINO acid sequence
- Publication
Nature Biotechnology, 2010, Vol 28, Issue 4, p322
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt0410-322