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- Title
Recurrent laryngeal squamous cell carcinoma: rTNM versus composite laryngeal recurrence staging system. Proposal for a modification of the CLRSS to improve patient classification.
- Authors
León, Xavier; López, Montserrat; García, Jacinto; Viza, Ignacio; Gich, Ignasi; Quer, Miquel
- Abstract
Background Based on the initial TNM stage of the tumor and the extension of recurrence, the composite laryngeal recurrence staging system (CLRSS) has been proposed as an alternative to the rTNM system for staging patients with recurrent laryngeal carcinoma. The objective of our study was to carry out an external validation of the CLRSS, and to evaluate a modified version of the original CLRSS, that we named CLRSS-2. Methods We conducted a retrospective analysis of 332 patients with recurrent laryngeal carcinoma treated in our center between 1985 and 2003. Results rTNM, CLRSS, and CLRSS-2 showed a monotonic prognostic gradient with increasing stage and produced significant differences in survival between stages. Discrepancies were detected in the cross-tabulation between rTNM and CLRSS. The CLRSS-2 achieved the best results in an objective comparison of the staging systems evaluated. Conclusion The CLRSS-2 was the best method to classify patients with a recurrent laryngeal carcinoma. © 2008 Wiley Periodicals, Inc. Head Neck, 2008
- Subjects
SQUAMOUS cell carcinoma; LARYNGEAL cancer; LARYNGITIS; TUMORS; CANCER patients
- Publication
Head & Neck, 2008, Vol 30, Issue 7, p939
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.20798