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- Title
Epidemiology of type 1 and type 2 diabetes mellitus in Kazakhstan: data from unified National Electronic Health System 2014–2019.
- Authors
Galiyeva, Dinara; Gusmanov, Arnur; Sakko, Yesbolat; Issanov, Alpamys; Atageldiyeva, Kuralay; Kadyrzhanuly, Kainar; Nurpeissova, Aiymzhan; Rakhimzhanova, Marzhan; Durmanova, Aigul; Sarria-Santamera, Antonio; Gaipov, Abduzhappar
- Abstract
Background: We aimed to explore descriptive epidemiology of T1 and T2 Diabetes Mellitus (DM) and to investigate demographic factors and comorbidities associated with all-cause mortality by aggregating and utilizing large-scale administrative healthcare data from the Unified National Electronic Health System (UNEHS) of Kazakhstan for 2014–2019 years period. Methods: A total of 475,539 individuals were included in the analyses. The median years of follow-up for Type 1 DM patients accounted for 4.7 years and 4.5 years in Type 2 DM patients. We used Kaplan-Meier and log-rank test to calculate failure function and differences in survival by age, sex, ethnicity, and comorbidities with all-cause mortality for Type 1 and Type 2 DM. Cox proportional hazards regression analysis was used to obtain crude and adjusted hazard ratios. Results: Prevalence of Type 1 and Type 2 DM increased 1.7 times from 2014 to 2019. Mortality of Type 1 and Type 2 DM also increased 4 times and 6 times from 2014 to 2019, respectively. Male sex, older age and Kazakh ethnicity were associated with a higher risk of all-cause death compared to females, younger age and other nationalities than Kazakh in patients with Type 1 and Type 2 DM. Coronary artery disease, diabetic nephropathy, stroke, amputations and neoplasms were associated with a higher risk of all-cause death. Conclusion: The prevalence and mortality rate of Type 1 and Type 2 DM increased during the years 2014–2019 in Kazakhstan. Male sex, older age and Kazakh ethnicity were associated with a higher risk of all-cause death compared to females, younger age and other nationalities than Kazakh. Coronary artery disease, diabetic nephropathy, stroke, amputations and neoplasms were associated with a higher risk of all-cause death.
- Subjects
KAZAKHSTAN; STROKE; LOG-rank test; AGE distribution; KAZAKHS; TYPE 1 diabetes; ACQUISITION of data; TYPE 2 diabetes; SEX distribution; KAPLAN-Meier estimator; DISEASE prevalence; CORONARY artery disease; MEDICAL records; DESCRIPTIVE statistics; SOCIODEMOGRAPHIC factors; AMPUTATION; TUMORS; COMORBIDITY; PROPORTIONAL hazards models; DIABETIC nephropathies; DISEASE complications
- Publication
BMC Endocrine Disorders, 2022, Vol 22, Issue 1, p1
- ISSN
1472-6823
- Publication type
Article
- DOI
10.1186/s12902-022-01200-6