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- Title
Predictive factors of recurrence after pediatric acute pericarditis.
- Authors
Krasic, Stasa; Prijic, Sergej; Ninic, Sanja; Borovic, Ruzica; Petrovic, Gordana; Stajevic, Mila; Nesic, Dejan; Dizdarevic, Ivan; Djordjevic, Nemanja; Vukomanovic, Vladislav
- Abstract
Objective: The predisposing factors for pericarditis recurrence in the pediatric population have not yet been established. This study aimed to define the risk factors for the unfavorable prognosis of pediatric acute pericarditis. Methods: This was a retrospective study that included all patients with acute pericarditis treated from 2011 to 2019 at a tertiary referent pediatric center. Results: The study included 72 children. Recurrence was observed in 22.2% patients. Independent risk factors for recurrence were: erythrocyte sedimentation rate ≥ 50 mm/h (p = 0.003, OR 186.3), absence of myocarditis (p = 0.05, OR 15.2), C-reactive protein ≥ 125 mg/L (p = 0.04, OR 1.5), and non-idiopathic etiology pericarditis (p = 0.003, OR 1.3). Corticosteroid treatment in acute pericarditis was associated with a higher recurrence rate than treatment with nonsteroid anti-inflammatory therapy (p = 0.04). Furthermore, patients treated with colchicine in the primary recurrence had lower recurrence rate and median number of repeated infections than those treated without colchicine (p = 0.04; p = 0.007, respectively). Conclusion: Independent risk factors for recurrence are absence of myocarditis, nonidiopathic etiology pericarditis, C-reactive protein ≥ 125 mg/L, and erythrocyte sedimentation
- Subjects
COLCHICINE; NONSTEROIDAL anti-inflammatory agents; PERICARDIUM diseases; ERYTHROCYTE disorders; CORTICOSTEROIDS
- Publication
Jornal de Pediatria, 2021, Vol 97, Issue 3, p335
- ISSN
0021-7557
- Publication type
Article
- DOI
10.1016/j.jped.2020.06.007