We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Highlight: integrative structural biology of dynamic macromolecular assemblies.
- Authors
Ficner, Ralf
- Abstract
Studying the three-dimensional structure and the dynamics of single, average-sized proteins has been mostly routine. However, due to the stunning complexity and flexibility of large multi-protein- and ribonucleoprotein complexes, classical biochemical, biophysical and structure determination methods - when used exclusively - do not meet the requirements to comprehend such systems in detail. During the last decade, tremendous progress has been made in the understanding of large macromolecular complexes.
- Subjects
BIOLOGY; NUCLEOCYTOPLASMIC interactions; NUCLEAR transport; RNA polymerase II; BIOMACROMOLECULES
- Publication
Biological Chemistry, 2023, Vol 404, Issue 8/9, p739
- ISSN
1431-6730
- Publication type
Article
- DOI
10.1515/hsz-2023-0256