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- Title
Association of lumbar artery narrowing, degenerative changes in disc and endplate and apparent diffusion in disc on postcontrast enhancement of lumbar intervertebral disc.
- Authors
Jaakko Niinimäki; Outi Parviainen; Marianne Haapea; Mari Kuisma; Risto Ojala; Raija Korpelainen; Osmo Tervonen; Miika Nieminen
- Abstract
Abstract Objective A decreased supply of nutrition to the intervertebral disc can lead to disc degeneration. Nutrient supply can be simulated in vivo by measuring gadolinium enhancement of the disc. We aimed to study the changes associated with disc degeneration that may have effect on the nutrition of the disc, i.e. lumbar artery narrowing, Modic changes, endplate defects, and apparent diffusion coefficient (ADC) in nucleus pulposus. Patients and methods Twenty male volunteers underwent a lumbar spine examination at 1.5 T for anatomical imaging, diffusion weighted imaging, magnetic resonance angiography, and for T1 relaxation time quantification of contrast enhancement of intervertebral disc. Results Enhancement of the disc increased with degeneration. Disc space narrowing associated strongly with the enhancement (Pearson’s correlation coefficient 0.46, P Conclusion Increased enhancement of a degenerated disc is associated mostly with disc space narrowing and with the presence of degenerative endplate changes and endplate defects.
- Subjects
LUMBAR vertebrae abnormalities; ARTERIAL abnormalities; NUTRITION; GADOLINIUM; ARTERIOGRAPHY; MAGNETIC resonance imaging; INTERVERTEBRAL disk diseases; PATIENTS
- Publication
MAGMA: Magnetic Resonance Materials in Physics, Biology & Medicine, 2009, Vol 22, Issue 2, p101
- ISSN
0968-5243
- Publication type
Article