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- Title
MotifNet: a web-server for network motif analysis.
- Authors
Smoly, Ilan Y.; Lerman, Eugene; Ziv-Ukelson, Michal; Yeger-Lotem, Esti
- Abstract
Summary: Network motifs are small topological patterns that recur in a network significantly more often than expected by chance. Their identification emerged as a powerful approach for uncovering the design principles underlying complex networks. However, available tools for network motif analysis typically require download and execution of computationally intensive software on a local computer. We present MotifNet, the first open-access web-server for network motif analysis. MotifNet allows researchers to analyze integrated networks, where nodes and edges may be labeled, and to search for motifs of up to eight nodes. The output motifs are presented graphically and the user can interactively filter them by their significance, number of instances, node and edge labels, and node identities, and view their instances. MotifNet also allows the user to distinguish between motifs that are centered on specific nodes and motifs that recur in distinct parts of the network.
- Subjects
INTERNET servers; IMAGE servers; MOTIF description (Movement notation); LABANOTATION; SPECTROSCOPE
- Publication
Bioinformatics, 2017, Vol 33, Issue 12, p1907
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btx056