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- Title
Fatal Basilar Artery Occlusion Under Dabigatran Occurring 13 Days After Femoral Embolectomy.
- Authors
Stöllberger, Claudia; Reiter, Markus; Schäffl-Doweik, Lilian; Finsterer, Josef
- Abstract
A male with atrial fibrillation for 30 years underwent embolectomy in his right leg at age 78 years. Postoperatively, he received enoxaparin 60 mg/twice a day (bid), and on day 5, phenprocoumon was started. The patient’s son, a general practitioner, changed phenprocoumon to dabigatran 110 mg/bid on day 8. Pain in his left calf induced readmission after 5 days. International normalized ratio was 2.5 and d-dimer was 20 μg/mL. Dabigatran was stopped and dalteparin 5000 International Units/bid and 40 μg alprostadil infusions were started. After 8 hours, he became comatose due to basilar artery occlusion and eventually died. This tragic case raises the issue of postoperative use of dabigatran, a recently introduced thrombin inhibitor.
- Subjects
STROKE prevention; ATRIAL fibrillation; DIAGNOSTIC imaging; VASCULAR surgery; EMBOLISMS; FEMORAL artery; EVALUATION of medical care; SURGICAL complications; UNITED States. Food &; Drug Administration; VASCULAR grafts; DRUG approval; BASILAR artery
- Publication
Vascular & Endovascular Surgery, 2012, Vol 46, Issue 4, p347
- ISSN
1538-5744
- Publication type
Article
- DOI
10.1177/1538574412443314