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- Title
Fetal vascular malperfusion, an update.
- Authors
Redline, Raymond W.; Ravishankar, Sanjita
- Abstract
Fetal vascular malperfusion is the most recent term applied to a group of placental lesions indicating reduced or absent perfusion of the villous parenchyma by the fetus. The most common etiology of malperfusion is umbilical cord obstruction leading to stasis, ischemia, and in some cases thrombosis. Other contributing factors may include maternal diabetes, fetal cardiac insuffciency or hyperviscosity, and inherited or acquired thrombophilias. Severe or high grade fetal vascular malperfusion is an important risk factor for adverse pregnancy outcomes including fetal growth restriction, fetal CNS injury, and stillbirth. Overall recurrence risk for subsequent pregnancies is low.
- Subjects
VASCULAR diseases; UMBILICAL cord abnormalities; FETAL distress; CEREBRAL palsy; PREGNANCY complications; PREVENTION; PATIENTS; DISEASE risk factors
- Publication
APMIS, 2018, Vol 126, Issue 7, p561
- ISSN
0903-4641
- Publication type
Article
- DOI
10.1111/apm.12849