We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Medicinal significance, pharmacological activities, and analytical aspects of solasodine: A concise report of current scientific literature.
- Authors
Patel, Kanika; Singh, Ravi B.; Patel, Dinesh K.
- Abstract
Abstract: Alkaloids are well known phytoconstituents for their diverse pharmacological properties. Alkaloids are found in all plant parts like roots, stems, leaves, flowers, fruits and seeds. Solasodine occurs as an aglycone part of glycoalkloids, which is a nitrogen analogue to sapogenins. Solanaceae family comprises of a number of plants with variety of natural products of medicinal significance mainly steroidal lactones, glycosides, alkaloids and flavanoids. It is a steroidal alkaloid based on a C27 cholestane skeleton. Literature survey reveals that solasodine has diuretic, anticancer, antifungal, cardiotonic, antispermatogenetic, antiandrogenic, immunomodulatory, antipyretic and various effects on central nervous system. Isolation and quantitative determination was achieved by several analytical techniques. Present review highlights the pharmacological activity of solasodine, with its analytical and tissue culture techniques, which may be helpful to the researchers to develop new molecules for the treatment of various disorders in the future.
- Subjects
SOLASODINE; PHARMACOLOGY; SCIENTIFIC literature; THERAPEUTIC use of alkaloids; PLANT roots; AGLYCONES; SAPOGENINS
- Publication
Journal of Acute Disease, 2013, Vol 2, Issue 2, p92
- ISSN
2221-6189
- Publication type
Article
- DOI
10.1016/S2221-6189(13)60106-7