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- Title
Decreased Quality of Life in Children With Hypothalamic Hamartoma and Treatment-Resistant Epilepsy.
- Authors
Park, Cleo; Wethe, Jennifer V.; Kerrigan, John F.
- Abstract
We evaluated health-related quality of life in patients with hypothalamic hamartoma, to see how it differs from that of children with more common neurologic disorders. We used the PedsQL 4.0, along with the Child Behavior Checklist, Hague Seizure Severity Scale, and Side Effects Scale, to evaluate presurgical patients with hypothalamic hamartoma and epilepsy (n = 21). The results were compared with those of age-matched cohorts with migraine (n = 19) and Benign Epilepsy with Central Temporal Spikes (n = 11). In comparison with the migraine group, the patients with hypothalamic hamartoma had decreased health-related quality of life across all domains of the PedsQL 4.0. Compared with the benign epilepsy group, the hypothalamic hamartoma cohort has a significantly lower score in School Function. Comorbid psychomotor retardation was predictive of lower quality of life. Research examining the efficacy of recently developed surgical treatments for hypothalamic hamartoma should include health-related quality of life as an outcome measure.
- Subjects
QUALITY of life; CHILDHOOD epilepsy; HAMARTOMA; HYPOTHALAMUS; CHILD Behavior Checklist; PSYCHOMOTOR disorders
- Publication
Journal of Child Neurology, 2013, Vol 28, Issue 1, p50
- ISSN
0883-0738
- Publication type
Article
- DOI
10.1177/0883073812439622