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Inefficient exogenous loading of a tapasin-dependent peptide onto HLA- B*44:02 can be improved by acid treatment or fixation of target cells.
Published in:
European Journal of Immunology, 2012, v. 42, n. 6, p. 1417, doi. 10.1002/eji.201141954
By:
- Stroobant, Vincent;
- Demotte, Nathalie;
- Luiten, Rosalie M.;
- Leonhardt, Ralf M.;
- Cresswell, Peter;
- Bonehill, Aude;
- Michaux, Alexandre;
- Ma, Wenbin;
- Mulder, Arend;
- Van den Eynde, Benoît J.;
- van der Bruggen, Pierre;
- Vigneron, Nathalie
Publication type:
Article
Conserved TCR usage by HLA-Cw*1601- restricted T cell clones recognizing melanoma antigens.
Published in:
International Immunology, 1996, v. 8, n. 9, p. 1463, doi. 10.1093/intimm/8.9.1463
By:
- Farina, Cinthia;
- van der Bruggen, Pierre;
- Boël, Pascale;
- Parmiani, Giorgio;
- Sensi, Marialuisa
Publication type:
Article
Estimation of the frequencies of anti-MAGE-3 cytolytic T-lymphocyte precursors in blood from individuals without cancer.
Published in:
International Journal of Cancer, 1998, v. 77, n. 4, p. 538, doi. 10.1002/(SICI)1097-0215(19980812)77:4<538::AID-IJC11>3.0.CO;2-2
By:
- Chaux, Pascal;
- Vantomme, Valérie;
- Coulie, Pierre;
- Boon, Thierry;
- van der Bruggen, Pierre
Publication type:
Article
Identification of HLA-A*0201-restricted CTL epitopes encoded by the tumor-specific MAGE-2 gene product.
Published in:
International Journal of Cancer, 1997, v. 73, n. 1, p. 125, doi. 10.1002/(SICI)1097-0215(19970926)73:1<125::AID-IJC19>3.0.CO;2-F
By:
- Visseren, Marjan J.W.;
- van der Burg, Sjoerd H.;
- van der Voort, Ellen I.H.;
- Brandt, Remco M.P.;
- Schrier, Peter I.;
- van der Bruggen, Pierre;
- Boon, Thierry;
- Melief, Cornelis J.M.;
- Kast, W. Martin
Publication type:
Article
Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice.
Published in:
Nature Biotechnology, 2015, v. 33, n. 4, p. 402, doi. 10.1038/nbt.3147
By:
- Obenaus, Matthias;
- Leitão, Catarina;
- Leisegang, Matthias;
- Chen, Xiaojing;
- Gavvovidis, Ioannis;
- van der Bruggen, Pierre;
- Uckert, Wolfgang;
- Schendel, Dolores J;
- Blankenstein, Thomas
Publication type:
Article
YopH prevents monocyte chemoattractant protein 1 expression in macrophages and T-cell proliferation through inactivation of the phosphatidylinositoI 3-kinase pathway.
Published in:
Molecular Microbiology, 2002, v. 45, n. 3, p. 805, doi. 10.1046/j.1365-2958.2002.03053.x
By:
- Sauvonnet, Nathalie;
- Lambermont, Isabelle;
- Bruggen, Pierre van der;
- Cornelis, Guy R.
Publication type:
Article
IRF1 and NF-kB Restore MHC Class I-Restricted Tumor Antigen Processing and Presentation to Cytotoxic T Cells in Aggressive Neuroblastoma.
Published in:
PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046928
By:
- Lorenzi, Silvia;
- Forloni, Matteo;
- Cifaldi, Loredana;
- Antonucci, Chiara;
- Citti, Arianna;
- Boldrini, Renata;
- Pezzullo, Marco;
- Castellano, Aurora;
- Russo, Vincenzo;
- van der Bruggen, Pierre;
- Giacomini, Patrizio;
- Locatelli, Franco;
- Fruci, Doriana
Publication type:
Article
How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions.
Published in:
Cancer Immunology, Immunotherapy, 2019, v. 68, n. 4, p. 631, doi. 10.1007/s00262-018-2170-8
By:
- Bruger, Annika M.;
- Dorhoi, Anca;
- Esendagli, Gunes;
- Barczyk-Kahlert, Katarzyna;
- van der Bruggen, Pierre;
- Lipoldova, Marie;
- Perecko, Tomas;
- Santibanez, Juan;
- Saraiva, Margarida;
- Van Ginderachter, Jo A.;
- Brandau, Sven
Publication type:
Article
Selective identification of HLA-DP4 binding T cell epitopes encoded by the MAGE-A gene family.
Published in:
Cancer Immunology, Immunotherapy, 2007, v. 56, n. 6, p. 807, doi. 10.1007/s00262-006-0230-y
By:
- Xiao-Fei Wang;
- Cohen, William M.;
- Castelli, Florence A.;
- Almunia, Christine;
- Lethé, Bernard;
- Pouvelle-Moratille, Sandra;
- Munier, Gaetan;
- Charron, Dominique;
- Ménez, André;
- Zarour, Hassan M.;
- van der Bruggen, Pierre;
- Busson, Marc;
- Maillère, Bernard
Publication type:
Article
A new MAGE-4 antigenic peptide recognized by cytolytic T lymphocytes on HLA–A24 carcinoma cells.
Published in:
Cancer Immunology, Immunotherapy, 2006, v. 55, n. 7, p. 867, doi. 10.1007/s00262-005-0053-2
By:
- Ottaviani, Sabrina;
- Colau, Didier;
- van der Bruggen, Pierre
Publication type:
Article
A MAGE-1 antigenic peptide recognized by human cytolytic T lymphocytes on HLA-A2 tumor cells.
Published in:
Cancer Immunology, Immunotherapy, 2005, v. 54, n. 12, p. 1214, doi. 10.1007/s00262-005-0705-2
By:
- Ottaviani, Sabrina;
- Yi Zhang;
- Boon, Thierry;
- van der Bruggen, Pierre
Publication type:
Article
MDSC in Mice and Men: Mechanisms of Immunosuppression in Cancer.
Published in:
Journal of Clinical Medicine, 2021, v. 10, n. 13, p. 2872, doi. 10.3390/jcm10132872
By:
- Vanhaver, Christophe;
- van der Bruggen, Pierre;
- Bruger, Annika M.
Publication type:
Article
Identification of an Immature Subset of PMN-MDSC Correlated to Response to Checkpoint Inhibitor Therapy in Patients with Metastatic Melanoma.
Published in:
Cancers, 2021, v. 13, n. 6, p. 1362, doi. 10.3390/cancers13061362
By:
- Gondois-Rey, Françoise;
- Paul, Magali;
- Alcaraz, Florence;
- Bourass, Sarah;
- Monnier, Jilliana;
- Malissen, Nausicaa;
- Grob, Jean-Jacques;
- Bruger, Annika M.;
- Van Der Bruggen, Pierre;
- Gaudy-Marqueste, Caroline;
- Olive, Daniel;
- Nilsson, Jonas
Publication type:
Article
Immune Suppression in Tumors as a Surmountable Obstacle to Clinical Efficacy of Cancer Vaccines.
Published in:
Cancers, 2011, v. 3, n. 3, p. 2904, doi. 10.3390/cancers3032904
By:
- Wieërs, Grégoire;
- Demotte, Nathalie;
- Godelaine, Danièle;
- van der Bruggen, Pierre
Publication type:
Article
New BAGE (B melanoma antigen) genes mapping to the juxtacentromeric regions of human chromosomes 13 and 21 have a cancer/testis expression profile.
Published in:
European Journal of Human Genetics, 2002, v. 10, n. 12, p. 833, doi. 10.1038/sj.ejhg.5200891
By:
- Ruault, Myriam;
- van der Bruggen, Pierre;
- Brun, Marie-Elisabeth;
- Boyle, Shelagh;
- Roizès, Gérard;
- Sario, Albertina De
Publication type:
Article
Immunosuppressive low-density neutrophils in the blood of cancer patients display a mature phenotype.
Published in:
Life Science Alliance, 2024, v. 7, n. 1, p. 1, doi. 10.26508/lsa.202302332
By:
- Vanhaver, Christophe;
- Nana, Frank Aboubakar;
- Delhez, Nicolas;
- Luyckx, Mathieu;
- Hirsch, Thibault;
- Bayard, Alexandre;
- Houbion, Camille;
- Dauguet, Nicolas;
- Brochier, Alice;
- van der Bruggen, Pierre;
- Bruger, Annika M.
Publication type:
Article
Tumor-specific shared antigenic peptides recognized by human T cells.
Published in:
Immunological Reviews, 2002, v. 188, n. 1, p. 51, doi. 10.1034/j.1600-065X.2002.18806.x
By:
- van der Bruggen, Pierre;
- Yi Zhang;
- Chaux, Pascal;
- Stroobant, Vincent;
- Panichelli, Christophe;
- Schultz, Erwin S.;
- Chapiro, Jacques;
- Van den Eynde, Benoit J.;
- Brasseur, Francis;
- Boon, Thierry
Publication type:
Article
HELIOS-expressing human CD8 T cells exhibit limited effector functions.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2023.1308539
By:
- Neyens, Damien;
- Hirsch, Thibault;
- Hadi, Achraqat Abdel Aziz Issa Abdel;
- Dauguet, Nicolas;
- Vanhaver, Christophe;
- Bayard, Alexandre;
- Wildmann, Claude;
- Luyckx, Mathieu;
- Squifflet, Jean-Luc;
- D'Hondt, Quentin;
- Duhamel, Céline;
- Huaux, Antoine;
- Montiel, Virginie;
- Dechamps, Mélanie;
- van der Bruggen, Pierre
Publication type:
Article
Phase 1/2 study of subcutaneous and intradermal immunization with a recombinant MAGE-3 protein in patients with detectable metastatic melanoma.
Published in:
International Journal of Cancer, 2005, v. 117, n. 4, p. 596, doi. 10.1002/ijc.21264
By:
- Kruit, Wim H.J.;
- van Ojik, Heidi H.;
- Brichard, Vincent G.;
- Escudier, Bernard;
- Dorval, Thierry;
- Dréno, Brigitte;
- Patel, Poulam;
- van Baren, Nicolas;
- Avril, Marie-Françoise;
- Piperno, Sophie;
- Khammari, Amir;
- Stas, Marguerite;
- Ritter, Gerd;
- Lethé, Bernard;
- Godelaine, Danièle;
- Brasseur, Francis;
- Zhang, Yi;
- van der Bruggen, Pierre;
- Boon, Thierry;
- Eggermont, Alexander M.M.
Publication type:
Article
A tyrosinase peptide presented by HLA-B35 is recognized on a human melanoma by autologous cytotoxic T lymphocytes.
Published in:
International Journal of Cancer, 1999, v. 83, n. 6, p. 755, doi. 10.1002/(SICI)1097-0215(19991210)83:6<755::AID-IJC10>3.0.CO;2-S
By:
- Morel, Sandra;
- Ooms, Annie;
- Van Pel, Aline;
- Wölfel, Thomas;
- Brichard, Vincent G.;
- Van der Bruggen, Pierre;
- Van den Eynde, Benoît J.;
- Degiovanni, Gérard
Publication type:
Article
A major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion.
Published in:
Nature Communications, 2016, v. 7, n. 7, p. 12242, doi. 10.1038/ncomms12242
By:
- Petit, Anne-Elisabeth;
- Demotte, Nathalie;
- Scheid, Benoît;
- Wildmann, Claude;
- Bigirimana, René;
- Gordon-Alonso, Monica;
- Carrasco, Javier;
- Valitutti, Salvatore;
- Godelaine, Danièle;
- van der Bruggen, Pierre
Publication type:
Article
Interleukins 1α and 1β secreted by some melanoma cell lines strongly reduce expression of MITF-M and melanocyte differentiation antigens.
Published in:
International Journal of Cancer, 2010, v. 127, n. 7, p. 1625, doi. 10.1002/ijc.25182
By:
- Kholmanskikh, Olga;
- van Baren, Nicolas;
- Brasseur, Francis;
- Ottaviani, Sabrina;
- Vanacker, Julie;
- Arts, Nathalie;
- van der Bruggen, Pierre;
- Coulie, Pierre;
- De Plaen, Etienne
Publication type:
Article
Frequent DNA hypomethylation of human juxtacentromeric BAGE loci in cancer.
Published in:
Genes, Chromosomes & Cancer, 2005, v. 43, n. 1, p. 11, doi. 10.1002/gcc.20155
By:
- Christoph Grunau;
- Cecilia Sanchez;
- Melanie Ehrlich;
- Pierre van der Bruggen;
- Winfried Hindermann;
- Carmen Rodriguez;
- Sophie Krieger;
- Louis Dubeau;
- Emerich Fiala;
- Albertina De Sario
Publication type:
Article
Lentivirally transduced dendritic cells as a tool for cancer immunotherapy.
Published in:
Journal of Gene Medicine, 2003, v. 5, n. 8, p. 654, doi. 10.1002/jgm.400
By:
- Karine Breckpot;
- Melissa Dullaers;
- Aude Bonehill;
- Sonja Van Meirvenne;
- Carlo Heirman;
- Catherine De Greef;
- Pierre van der Bruggen;
- Kris Thielemans
Publication type:
Article
Dendritic Cells Loaded With mRNA Encoding Full-length Tumor Antigens Prime CD4<sup>+</sup> and CD8<sup>+</sup> T Cells in Melanoma Patients.
Published in:
Molecular Therapy, 2012, v. 20, n. 5, p. 1063, doi. 10.1038/mt.2012.11
By:
- Van Nuffel, An MT;
- Benteyn, Daphné;
- Wilgenhof, Sofie;
- Pierret, Lauranne;
- Corthals, Jurgen;
- Heirman, Carlo;
- van der Bruggen, Pierre;
- Coulie, Pierre G;
- Neyns, Bart;
- Thielemans, Kris;
- Bonehill, Aude
Publication type:
Article
Side-by-Side Comparison of Lentivirally Transduced and mRNA-Electroporated Dendritic Cells: Implications for Cancer Immunotherapy Protocols
Published in:
Molecular Therapy, 2004, v. 10, n. 4, p. 768, doi. 10.1016/j.ymthe.2004.07.017
By:
- Dullaers, Melissa;
- Breckpot, Karine;
- Van Meirvenne, Sonja;
- Bonehill, Aude;
- Tuyaerts, Sandra;
- Michiels, Annelies;
- Straetman, Lieven;
- Heirman, Carlo;
- De Greef, Catherine;
- Van Der Bruggen, Pierre;
- Thielemans, Kris
Publication type:
Article
Galectin-3 captures interferon-gamma in the tumor matrix reducing chemokine gradient production and T-cell tumor infiltration.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00925-6
By:
- Gordon-Alonso, Monica;
- Hirsch, Thibault;
- Wildmann, Claude;
- van der Bruggen, Pierre
Publication type:
Article
Mesothelioma response to carbon nanotubes is associated with an early and selective accumulation of immunosuppressive monocytic cells.
Published in:
Particle & Fibre Toxicology, 2016, p. 1, doi. 10.1186/s12989-016-0158-0
By:
- Huaux, François;
- de Bousies, Virginie d'Ursel;
- Parent, Marie-Astrid;
- Orsi, Micaela;
- Uwambayinema1, Francine;
- Devosse, Raynal;
- Ibouraadaten, Saloua;
- Yakoub, Yousof;
- Panin, Nadtha;
- Palmai-Pallag, Mihaly;
- van der Bruggen, Pierre;
- Bailly, Christian;
- Marega, Riccardo;
- Marbaix, Etienne;
- Lison, Dominique
Publication type:
Article
TCR Gene Transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 Epitopes as Melanoma-Specific Immune Targets.
Published in:
2012
By:
- Straetemans, Trudy;
- van Brakel, Mandy;
- van Steenbergen, Sabine;
- Broertjes, Marieke;
- Drexhage, Joost;
- Hegmans, Joost;
- Lambrecht, Bart N;
- Lamers, Cor;
- Bruggen, Pierre van Der;
- Coulie, Pierre G;
- Debets, Reno
Publication type:
Journal Article
TCR Gene Transfer:MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 Epitopes as Melanoma-Specific Immune Targets.
Published in:
Clinical & Developmental Immunology, 2012, p. 1, doi. 10.1155/2012/586314
By:
- Straetemans, Trudy;
- Van Brakel, Mandy;
- Van Steenbergen, Sabine;
- Broertjes, Marieke;
- Drexhage, Joost;
- Hegmans, Joost;
- Lambrecht, Bart N.;
- Lamers, Cor;
- Der Bruggen, Pierre van;
- Coulie, Pierre G.;
- Debet, Reno
Publication type:
Article
Expression and prognostic relevance of MAGE-A3 and MAGE-C2 in non-small cell lung cancer.
Published in:
Oncology Letters, 2017, v. 13, n. 3, p. 1609, doi. 10.3892/ol.2017.5665
By:
- XINFENG CHEN;
- LIPING WANG;
- JINYAN LIU;
- LAN HUANG;
- LI YANG;
- QUN GAO;
- XIAOJUAN SHI;
- JIEYAO LI;
- FENG LI;
- ZHEN ZHANG;
- SONG ZHAO;
- BIN ZHANG;
- VAN DER BRUGGEN, PIERRE;
- YI ZHANG
Publication type:
Article
Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy.
Published in:
Nature Reviews Cancer, 2014, v. 14, n. 2, p. 135, doi. 10.1038/nrc3670
By:
- Coulie, Pierre G.;
- Van den Eynde, Benoît J.;
- van der Bruggen, Pierre;
- Boon, Thierry
Publication type:
Article
Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy.
Published in:
2014
By:
- Coulie, Pierre G;
- Van den Eynde, Benoît J;
- van der Bruggen, Pierre;
- Boon, Thierry
Publication type:
journal article
Comparison of stable human Treg and Th clones by transcriptional profiling.
Published in:
European Journal of Immunology, 2009, v. 39, n. 3, p. 869, doi. 10.1002/eji.200838807
By:
- Stockis, Julie;
- Fink, Wolfram;
- François, Violaine;
- Connerotte, Thierry;
- de Smet, Charles;
- Knoops, Laurent;
- van der Bruggen, Pierre;
- Boon, Thierry;
- Coulie, Pierre G.;
- Lucas, Sophie
Publication type:
Article
A polyclonal anti-vaccine CD4 T cell response detected with HLA-DP4 multimers in a melanoma patient vaccinated with MAGE-3.DP4-peptide-pulsed dendritic cells.
Published in:
European Journal of Immunology, 2005, v. 35, n. 4, p. 1066, doi. 10.1002/eji.200425847
By:
- Zhang, Yi;
- Renkvist, Nicolina;
- Sun, Zhaojun;
- Schuler-Thurner, Beatrice;
- Glaichenhaus, Nicolas;
- Schuler, Gerold;
- Boon, Thierry;
- van der Bruggen, Pierre;
- Colau, Didier
Publication type:
Article
A reversible functional defect of CD8.
Published in:
European Journal of Immunology, 2002, v. 32, n. 6, p. 1688, doi. 10.1002/1521-4141(200206)32:6<1688::AID-IMMU1688>3.0.CO;2-9
By:
- Demotte, Nathalie;
- Colau, Didier;
- Ottaviani, Sabrina;
- Godelaine, Danièle;
- Pel, Aline Van;
- Boon, Thierry;
- Bruggen, Pierre van der
Publication type:
Article
A MAGE-1 peptide recognized on HLA-DR15 by CD4.
Published in:
European Journal of Immunology, 2001, v. 31, n. 6, p. 1910, doi. 10.1002/1521-4141(200106)31:6<1910::AID-IMMU1910>3.0.CO;2-K
By:
- Chaux, Pascal;
- Lethé, Bernard;
- Van Snick, Jacques;
- Corthals, Jurgen;
- Schultz, Erwin S.;
- Cambiaso, César L.;
- Boon, Thierry;
- van der Bruggen, Pierre
Publication type:
Article
A MAGE-A4 peptide presented by HLA-A2 is recognized by cytolytic T lymphocytes.
Published in:
European Journal of Immunology, 1999, v. 29, n. 10, p. 3329, doi. 10.1002/(SICI)1521-4141(199910)29:10<3329::AID-IMMU3329>3.0.CO;2-7
By:
- Duffour, Marie-Thérèse;
- Chaux, Pascal;
- Lurquin, Christophe;
- Cornelis, Guy;
- Boon, Thierry;
- Van der Bruggen, Pierre
Publication type:
Article
Effect of epitope flanking residues on the presentation of N-terminal cytotoxic T lymphocyte epitopes.
Published in:
European Journal of Immunology, 1999, v. 29, n. 7, p. 2213, doi. 10.1002/(SICI)1521-4141(199907)29:07<2213::AID-IMMU2213>3.0.CO;2-8
By:
- Gileadi, Uzi;
- Gallimore, Awen;
- Van der Bruggen, Pierre;
- Cerundolo, Vincenzo
Publication type:
Article
Major histocompatibility complex class I presentation of exogenous soluble tumor antigen fused to the B-fragment of Shiga toxin.
Published in:
European Journal of Immunology, 1998, v. 28, n. 9, p. 2726, doi. 10.1002/(SICI)1521-4141(199809)28:09<2726::AID-IMMU2726>3.0.CO;2-W
By:
- Lee, Ren-Shiang;
- Tartour, Eric;
- Van der Bruggen, Pierre;
- Vantomme, Valérie;
- Joyeux, Isabelle;
- Goud, Bruno;
- Fridman, Wolf Herman;
- Johannes, Ludger
Publication type:
Article
Control of B cell lymphoma recognition via natural killer inhibitory receptors implies a role for human Vγ9/Vδ2 T cells in tumor immunity.
Published in:
European Journal of Immunology, 1997, v. 27, n. 12, p. 3368, doi. 10.1002/eji.1830271236
By:
- Fisch, Paul;
- Meuer, Eva;
- Pende, Daniela;
- Rothenfußer, Simon;
- Viale, Oriane;
- Kock, Sylvia;
- Ferrone, Soldano;
- Fradelizi, Didier;
- Klein, George;
- Moretta, Lorenzo;
- Rammensee, Hans-Georg;
- Boon, Thierry;
- Coulie, Pierre;
- van der Bruggen, Pierre
Publication type:
Article
A peptide encoded by human gene MAGE-3 and presented by HLA-A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE-3.
Published in:
European Journal of Immunology, 1994, v. 24, n. 12, p. 3038, doi. 10.1002/eji.1830241218
By:
- van der Bruggen, Pierre;
- Bastin, Judy;
- Gajewski, Thomas;
- Coulie, Pierre G.;
- Boël, Pascale;
- De Smet, Charles;
- Traversari, Catia;
- Townsend, Alain;
- Boon, Thierry
Publication type:
Article
Autologous cytolytic T lymphocytes recognize a MAGE-1 nonapeptide on melanomas expressing HLA-Cw* 1601.
Published in:
European Journal of Immunology, 1994, v. 24, n. 9, p. 2134, doi. 10.1002/eji.1830240930
By:
- Bruggen, Pierre Van Der;
- Szikora, Jean-Pierre;
- Boël, Pascale;
- Wildmann, Claude;
- Somville, Michel;
- Sensi, Marialuisa;
- Boon, Thierry
Publication type:
Article
Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15303-y
By:
- Renard, Henri-François;
- Tyckaert, François;
- Lo Giudice, Cristina;
- Hirsch, Thibault;
- Valades-Cruz, Cesar Augusto;
- Lemaigre, Camille;
- Shafaq-Zadah, Massiullah;
- Wunder, Christian;
- Wattiez, Ruddy;
- Johannes, Ludger;
- van der Bruggen, Pierre;
- Alsteens, David;
- Morsomme, Pierre
Publication type:
Article

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