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- Title
PREMATURE RUPTURE OF MEMBRANES; DIAGNOSTIC ACCURACY OF β-hCG TEST IN VAGINAL WASHINGS TAKING AMNIOTIC FLUID POOLING AS GOLD STANDARD OF DIAGNOSING PRON.
- Authors
Azam, Azmeena; Husnain, Hafiz Maoz; Marryum, Iqra
- Abstract
Background: Pre-labour rupture of the membranes is one of the most common clinical presentations in an obstetric setting. Early diagnosis is a major challenge faced by every obstetrician and key to effective management and prevention of complications. As a result of PROM, amniotic fluid that provides protection to the developing fetus is lost, exposing it to the outside environment. β-hCG is a hormone secreted by syncytiotrophoblasts found in amniotic fluid that can be studied for the evaluation of PROM. Objectives: To find the Diagnostic Accuracy of β human chorionic gonadotrophin test in vaginal washings taking amniotic fluid pooling as gold standard of diagnosing PROM. Study Design: Cross-sectional study. Setting: Unit II, Department of Obstetrics & Gynecology, Lahore General Hospital, Lahore. Period: Three months from January 2017 to March 2017. Material and methods: Females of age 18-40 years with gestational age ≥36weeks (calculated by LMP) complaining of PV leaking were included in the study. Samples for β-hCG measurements were taken after informed consent. A β-hCG kit (Acu-check) was used for detection of β-hCG in vaginal fluid washings of pregnant women. Results: Diagnostic accuracy of β-hCG test was 91.66%. Sensitivity and specificity of β-hCG test was 86.66% and 96.66%. Positive predictive and negative predictive value was 96.29% and 87.87% respectively. Conclusion: Results of this study showed that for diagnosis of patients having PROM, beta human chorionic gonadotrophin (β-hCG) is a reliable, easy and quick test.
- Subjects
AMNIOTIC liquid examination; VAGINAL discharge; PREGNANT women; GONADOTROPIN regulation; FLUIDITY of biological membranes; PHYSIOLOGY
- Publication
Professional Medical Journal, 2018, Vol 25, Issue 2, p168
- ISSN
1024-8919
- Publication type
Article
- DOI
10.29309/TPMJ/18.4219