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- Title
Case series of COVID-19 infection in pregnancy complicated by ketoacidosis and symptomatic breathlessness.
- Authors
Thorne, Iona; Steele, Samantha; Martineau, Marcus; Girling, Joanna
- Abstract
Background: The differential diagnosis of acute shortness of breath in a pregnant woman with COVID-19 is broad. Pregnancy is a ketosis-prone state, which can result in metabolic acidosis and tachypnoea. Methods: We describe four pregnant women with COVID-19 and breathlessness where ketoacidosis was found to contribute to symptomatic tachypnoea. Results: One patient did not have associated COVID-19 pneumonitis, but presented with severe tachypnoea and metabolic acidosis; three women had pneumonitis and metabolic acidosis. Corrective treatment for the metabolic abnormalities resulted in resolution of the ketoacidosis in all cases. No women had coexistent diabetes. Conclusion: This is the first series of COVID-19 in pregnancy complicated by ketoacidosis and symptomatic tachypnoea. Ketoacidosis associated with COVID-19 is an important cause of tachypnoea requiring specific treatment, which should not be overlooked. Potential mechanisms for this are discussed with a framework for interpretation of blood gas results during pregnancy.
- Subjects
PNEUMONIA; COVID-19; TACHYPNEA; BLOOD gases analysis; DYSPNEA; ACIDOSIS; PREGNANCY
- Publication
Obstetric Medicine (1753-495X), 2022, Vol 15, Issue 1, p50
- ISSN
1753-495X
- Publication type
Article
- DOI
10.1177/1753495X211024511