We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Review of cobalamin status and disorders of cobalamin metabolism in dogs.
- Authors
Kather, Stefanie; Grützner, Niels; Kook, Peter H.; Dengler, Franziska; Heilmann, Romy M.
- Abstract
Disorders of cobalamin (vitamin B12) metabolism are increasingly recognized in small animal medicine and have a variety of causes ranging from chronic gastrointestinal disease to hereditary defects in cobalamin metabolism. Measurement of serum cobalamin concentration, often in combination with serum folate concentration, is routinely performed as a diagnostic test in clinical practice. While the detection of hypocobalaminemia has therapeutic implications, interpretation of cobalamin status in dogs can be challenging. The aim of this review is to define hypocobalaminemia and cobalamin deficiency, normocobalaminemia, and hypercobalaminemia in dogs, describe known cobalamin deficiency states, breed predispositions in dogs, discuss the different biomarkers of importance for evaluating cobalamin status in dogs, and discuss the management of dogs with hypocobalaminemia.
- Subjects
METABOLIC disorders; VITAMIN B12; DOGS; DOG breeds; GASTROINTESTINAL diseases; DOG breeding
- Publication
Journal of Veterinary Internal Medicine, 2020, Vol 34, Issue 1, p13
- ISSN
0891-6640
- Publication type
Article
- DOI
10.1111/jvim.15638