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- Title
Polyvinylpyrrolidone-passivated fluorescent iron oxide quantum dots for turn-off detection of tetracycline in biological fluids.
- Authors
Sudewi, Sri; Chabib, Lutfi; Zulfajri, Muhammad; Gedda, Gangaraju; Huang, Genin G.
- Abstract
Tetracycline is an antibiotic that has been prescribed for COVID-19 treatment, raising concerns about antibiotic resistance after long-term use. This study reported fluorescent polyvinylpyrrolidone-passivated iron oxide quantum dots (IO QDs) for detecting tetracycline in biological fluids for the first time. The as-prepared IO QDs have an average size of 2.84 nm and exist a good stability under different conditions. The IO QDs' tetracycline detection performance could be attributed to a combination of static quenching and inner filter effect. The IO QDs displayed high sensitivity and selectivity toward tetracycline and achieved a good linear relationship with the corresponding detection limit being 91.6 nM.
- Subjects
BODY fluid analysis; EXPERIMENTAL design; COVID-19; TETRACYCLINE; SPECTROPHOTOMETERS; LIQUID chromatography; IRON oxide nanoparticles; MASS spectrometry; RESEARCH funding; DRUG resistance in microorganisms; URINALYSIS
- Publication
Journal of Food & Drug Analysis, 2023, Vol 31, Issue 1, p177
- ISSN
1021-9498
- Publication type
Article
- DOI
10.38212/2224-6614.3440