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- Title
Improved outcomes after low-concentration hypochlorous acid nasal irrigation in pediatric chronic sinusitis.
- Authors
Cho, Hyung‐Ju; Min, Hyun Jin; Chung, Hyo Jin; Park, Do‐Yang; Seong, Sang Yeob; Yoon, Joo‐Heon; Lee, Jeung‐Gweon; Kim, Chang‐Hoon
- Abstract
<bold>Objectives/hypothesis: </bold>We aimed to evaluate the effectiveness of low-concentration hypochlorous acid (HOCl) nasal irrigation compared to isotonic normal saline for pediatric chronic rhinosinusitis.<bold>Study Design: </bold>This was a randomized, prospective, active-controlled study.<bold>Methods: </bold>This study investigated the effectiveness of 4 weeks of low-concentration hypochlorous irrigation by analyzing five categorized subjective symptoms and x-ray findings in pediatric patients with rhinosinusitis. Thirty-seven patients were enrolled, and 26 patients successfully completed the study.<bold>Results: </bold>Total symptom scores significantly improved with both HOCl and normal saline nasal irrigation, but there was no difference between the two groups. X-ray scores also improved in both groups; improvement was much greater in the HOCl group than the placebo group.<bold>Conclusions: </bold>Nasal irrigation with HOCl is an effective adjuvant treatment compared to isotonic normal saline for pediatric sinusitis.<bold>Level Of Evidence: </bold>1b.
- Subjects
SINUSITIS in children; HYPOCHLORITES; NASAL irrigation; PHYSIOLOGIC salines; PEDIATRIC otolaryngology; THERAPEUTICS; SINUSITIS treatment; CHRONIC diseases; COMPARATIVE studies; LONGITUDINAL method; RESEARCH methodology; MEDICAL cooperation; RESEARCH; EVALUATION research; RANDOMIZED controlled trials; TREATMENT effectiveness
- Publication
Laryngoscope, 2016, Vol 126, Issue 4, p791
- ISSN
0023-852X
- Publication type
journal article
- DOI
10.1002/lary.25605