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- Title
Anticytokine Autoantibodies in Infectious Diseases: A Practical Overview.
- Authors
Arts, Rob J. W.; Janssen, Nico A. F.; van de Veerdonk, Frank L.
- Abstract
Anticytokine autoantibodies (ACAAs) are a fascinating group of antibodies that have gained more and more attention in the field of autoimmunity and secondary immunodeficiencies over the years. Some of these antibodies are characterized by their ability to target and neutralize specific cytokines. ACAAs can play a role in the susceptibility to several infectious diseases, and their infectious manifestations depending on which specific immunological pathway is affected. In this review, we will give an outline per infection in which ACAAs might play a role and whether additional immunomodulatory treatment next to antimicrobial treatment can be considered. Finally, we describe the areas for future research on ACAAs.
- Subjects
AUTOANTIBODIES; COMMUNICABLE diseases; IMMUNOSPECIFICITY; AUTOIMMUNITY; IMMUNOGLOBULINS; FC receptors
- Publication
International Journal of Molecular Sciences, 2024, Vol 25, Issue 1, p515
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms25010515