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- Title
Lifestyle and vitamin D dosage in women with breast cancer.
- Authors
Dias, Manoela Maciel Dos Santos; Queiroz, Andréia Ribeiro; Suhett, Lara Gomes; Freitas, Renata Nascimento; De Paula, Sérgio Oliveira; Peluzio, Maria do Carmo Gouveia; dos Santos Dias, Manoela Maciel; Pessoa, Milene Cristine; Ribeiro Queiroz, Andréia; Gomes Suhett, Lara; Gouveia Peluzio, Maria do Carmo; Nogueira Oliveira-Sediyama, Catarina Maria; Nascimento Freitas, Renata; Oliveira de Paula, Sérgio; Oliveira Sediyama, Catarina Maria
- Abstract
<bold>Introduction: </bold>The prevention strategy of breast cancer is still the key factor for early diagnosis and the most effective method for tracking the disease.<bold>Objective: </bold>This study aimed to evaluate the association vitamin D level with breast cancer in women.<bold>Methods: </bold>This hospital case-control study was conducted with 181 women with breast cancer and 197 healthy controls. Vitamin D status, calcium, phosphorus and PTH serum dosage and data collection related to lifestyle and patient's history, besides anthropometric measurements were performed. Univariate analysis (Chi-square and raw odds ratio) and multivariate analysis were performed through multivariate logistic regression.<bold>Results: </bold>This study shows a higher value of vitamin D in health controls (26.9 mg/dL) than in breast cancer women (24.8 mg/dL). Higher numbers of women with sufficient vitamin D status (34.85%) were found in control group than cancer group. Using the multiple logistic regression model, the family history of breast cancer (OR 36.37, 95%CI 4.75-278.50) and menopause (OR 5.17, 95% CI 2.72-9.80) had a direct association with breast cancer, while the level of vitamin D (OR 0.95, 95%CI 0.91-0.99) and moderate physical activity (OR 0.31, 95%CI 0.10-0.93) maintained the inverse associations with the disease.<bold>Conclusion: </bold>Vitamin D status and the practice of moderate physical activity were considered protective factors for breast cancer. However, menopause and family history of breast cancer were considered a risk factor for breast cancer.
- Subjects
BRAZIL; VITAMIN D; BREAST cancer diagnosis; MENOPAUSE; PHYSICAL activity; LOGISTIC regression analysis; BREAST tumors; DIETARY calcium; VITAMINS; SOCIOECONOMIC factors; LIFESTYLES; CASE-control method
- Publication
Nutrición Hospitalaria, 2016, Vol 33, Issue 5, p1179
- ISSN
0212-1611
- Publication type
journal article
- DOI
10.20960/nh.584