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- Title
A Convenient Methods for Synthetic Isomeric Structures of Pyrimido-1,2-4-triazine Derivatives as Biocidal Agents.
- Authors
El-Mahdy, Kamelia M.; Abdel-Rahman, Reda M.
- Abstract
Some new isomeric structures of pyrimido[2,1-c][1,2,4]triazines 4-8 and 10-14 have been synthesized via the ring closure reactions of 2-hydrazinyl-1-methylpyrimidine 3 and/or 2-hydrazinopyrimidine 9 with acyclic and cyclic oxygen compounds under various conditions. Structures of the targets have been established from their elemental analyses and spectral data (UV, IR, ¹H/13C NMR and mass spectrometry). Most of the obtained compounds were evaluated as antimicrobial agents and compared with pipericillin and mycostatine as standard antibiotics. Only compound 7 had highly biocidal effects.
- Subjects
ISOMERS; TRIAZINES; ANTI-infective agents; ANTIBIOTICS; BIOCIDES; MASS spectrometry; NUCLEAR magnetic resonance spectroscopy
- Publication
Acta Chimica Slovenica, 2011, Vol 58, Issue 4, p755
- ISSN
1318-0207
- Publication type
Article