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- Title
Synthesis of β-(о-hydroxybenzyl)pyridines by three-component condensation of ammonia, carbonyl-substituted 4Н-chromenes, and СН acids.
- Authors
Osipov, Dmitry V.; Osyanin, Vitaly A.; Klimochkin, Yuri N.
- Abstract
A series of pyridine derivatives containing a 2-hydroxybenzyl or (2-hydroxynaphthalen-1-yl)methyl substituent were obtained by treating carbonyl-substituted 4Н-chromenes and 1Н-benzo[f]chromenes with ammonia and 1,3-dicarbonyl compounds or aromatic ketones as a result of the carbo-Michael reaction, chromane ring opening, and cyclodehydration.
- Subjects
PYRIDINE synthesis; CONDENSATION reactions; AMMONIA; SUBSTITUENTS (Chemistry); CARBONYL compounds
- Publication
Chemistry of Heterocyclic Compounds, 2018, Vol 54, Issue 12, p1121
- ISSN
0009-3122
- Publication type
Article
- DOI
10.1007/s10593-019-02402-y