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- Title
Evaluation of the Systemic Immune Inflammatory Response in Cases Infected with Helicobacter Pylori.
- Authors
Koç, Zeynep; Sürücü, Merve; Taşkın, Hilal Çakır; Oktar, Didem; Aladağ, Nazire; Koç, Şanver; Tuna, Müjgan Kaya; Böyük, Banu; Akın, Seydahmet; Keskin, Özcan
- Abstract
Objectives: The effectiveness of systemic immune inflammation index (SII), which is a practical, new, and useful marker in indicating inflammation, in various malignant and non-malignant diseases has been shown. In the present study, it was aimed to examine the correlation between Helicobacter pylori (HP)+, which causes chronic infection and inflammation, and SII. Methods: A total of 88 HP+ cases and 154 HP− control cases were included our retrospective, randomized, and controlled study. HP± was assessed according to the endoscopic biopsy reports of cases. All secondary causes that may lead to inflammation were excluded from the study. The SI level of the case and control groups was calculated (absolute neutrophil × absolute platelet/absolute lymphocyte). Results: In our study, no significant correlation between HP+, a chronic infection, and SII could not be shown (p>0.05). It was detected that HP+ was more common in young ages (p<0.05). Conclusion: The results of our study suggest that SII may not be a useful marker in indicating HP+ as we could not find a significant correlation between SII and HP+.
- Subjects
BIOMARKERS; HELICOBACTER pylori; INFLAMMATION; SYSTEMIC inflammatory response syndrome; RETROSPECTIVE studies; ACQUISITION of data; CASE-control method; QUANTITATIVE research; MANN Whitney U Test; INFECTION; RANDOMIZED controlled trials; T-test (Statistics); PEARSON correlation (Statistics); MEDICAL records; DESCRIPTIVE statistics; CHI-squared test; STATISTICAL sampling; DATA analysis software; HELICOBACTER diseases
- Publication
Bosphorus Medical Journal / Boğaziçi Tıp Dergisi, 2023, Vol 10, Issue 3, p126
- ISSN
2149-0287
- Publication type
Article
- DOI
10.14744/bmj.2023.03164